Mapping and Quantifying Lymphatic Drainage of the Arm's Alternate Pathway
Beth Israel Deaconess Medical Center · with National Heart, Lung, and Blood Institute (NHLBI) · NCT05253352
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · Women only
- Healthy volunteers
- Accepted
- Study type
- Observational
- Target enrollment
- 142
- US sites recruiting
- 1
- Study start
- April 1, 2022
- Record last updated
- March 11, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Using indocyanine green (ICG) lymphography and lymphoscintigraphy with SPECT/CT imaging, the aim is to evaluate the anatomy of the lymphatic system pathway in two separate populations: healthy female volunteers and women with a history of breast cancer who did not develop lymphedema.
Conditions: Lymphatic System
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Female
- History of breast cancer treatment including ALND - defined by removal of >=10 lymph nodes - more than 2 years before study participation
- Ability to understand the protocol and willingness to participate
- At least 18 years of age
Exclusion Criteria
- Prior history of bilateral lymph node surgery
- Prior history of other surgical procedures of the affected upper extremity besides the axillary management for breast cancer treatment
- Prior history of chronic inflammatory conditions (e.g. rheumatoid arthritis)
- Prior history of filarial infections
- Prior history of lymphedema
- Patient-reported pregnancy
- Patients who are breastfeeding
- Iodine allergy
- Prior history of upper extremity deep vein thrombosis
- Prior history of congestive heart failure
- Prior history of venous thoracic outlet syndrome
- Current active cancer
Recruiting US locations
Beth Israel Deaconess Medical Center
Boston, MA 02215
Site contact: Dhruv Singhal, MD · 617-632-7855
Study contacts (from the official record)
- Angela Chen, BS · 6176327043 · achen22@bidmc.harvard.edu
Similar studies in Massachusetts
All healthy volunteers studies in Massachusetts →- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Novartis Pharmaceuticals
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingHealthy volunteersPhase 1
Study to Evaluate the Safety, Pharmacokinetic, and Pharmacodynamic Effects of MY006 in Healthy Volunteers and Patients With Peanut Allergy
Mabylon AG
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingHealthy volunteersPhase 1
Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HTX-001
Haya Therapeutics, Inc.
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Boston, MA + 49 other US sites
- Eligibility basics
- Ages 60+