Monetary Incentive Delay Task for Probing Reward-related Neural Processes
Stony Brook University · NCT06369623
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 14–17 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 300
- US sites recruiting
- 1
- Study start
- April 6, 2024
- Record last updated
- May 15, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
150 males and 150 females ages 14-17 years-old will be enrolled in an observational, longitudinal study. There are three planned in-person visits: a baseline assessment, an 18-month follow-up, and a 36-month follow-up. The in-person visits will include assessment of substance use and other individual differences (e.g., reward function, psychiatric history), neuromelanin-sensitive MRI, as well as functional brain activation collected while the participant is at rest (resting-state fMRI) and while the participant completes a Monetary Incentive Delay task. Subjects will also be asked to complete past 90-day substance use assessments remotely every 90 days for 36 months.
Being studied: Monetary Incentive Delay Task
Conditions: Adolescent Development
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Males and females ages 14-17 years-old;
- English-speaking for assent and interview completion;
- Capacity to provide assent.
- For parents, the inclusion criteria will be willing and capacity to provide parental permission/consent.
Exclusion Criteria
- current (within 6 months) use of medication that may affect cerebral function
- history of severe medical or neurological illness, including stroke or seizure;
- history of head trauma with loss of consciousness;
- presence of metal in the body;
- pregnancy or breastfeeding;
- recent drug or alcohol use determined by positive urine toxicology or breathalyzer (to validate self-report assessment of substance use history);
- lifetime use of psychotropic or other medication that could likely influence dopamine function, namely stimulant medication or antipsychotic medication, except a subgroup of 25 youth with history of prescribed stimulant medication and a subgroup of 15 youth with history antipsychotic medication will be enrolled for comparison purposes.
Recruiting US locations
Stony Brook Medicine
Stony Brook, NY 11794
Site contact: Greg Perlman, PhD · 631-638-1922 · greg.perlman@stonybrookmedicine.edu
Study contacts (from the official record)
- Greg Perlman, PhD · 1-631-638-1922 · greg.perlman@stonybrookmedicine.edu
- Lu-Ann Kozlowski, BSN · 1-631-632-9036 · lu-ann.kozlowski@stonybrook.edu
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