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Multimodal Musical Stimulation for Healthy Neurocognitive Aging

Northeastern University · NCT06229093

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–95 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
100
US sites recruiting
1
Study start
December 11, 2022
Record last updated
July 10, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This is a Stage I randomized, sham-controlled trial on the effects of multimodal musical stimulation on working memory in aging. Neurologically healthy older and younger adults will be tested on working memory and electroencephalography in the first randomized controlled trial of music as a form of brain stimulation, with multimodal musical stimulation and control stimulation conditions. Results will test the causal role of oscillatory mechanisms of the brain on cognition, and will lay the groundwork to the first musical, neurophysiologically targeted, brain-stimulation device for reversing cognitive decline in aging.

Being studied: Gamma; Synchrony

Conditions: Aging

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • normal or corrected-to-normal vision
  • no more than mild hearing loss
  • no recent history of neurological or psychiatric disorders, including mood disorders or use of medications that may affect cognition or responsiveness to music.

Exclusion Criteria

  • moderate or severe hearing loss (40+ dB)
  • visual impairment (including color blindness) that cannot be corrected with glasses or contacts
  • recently changed dosage of cholinesterase inhibitors or psychotropic medication
  • recent history of psychotic or schizophrenic episodes
  • major neurologic diagnosis or other condition that might impair cognition or confound assessments (dementia, ADRD; Parkinson's disease, stroke, brain injury, epilepsy, or recent cardiovascular or neurovascular event)
  • recent history of serious physical trauma or diagnosis of serious chronic health condition requiring medical treatment and monitoring .

Recruiting US locations

  • Northeastern University

    Boston, MA 02115

    Site contact: Corinna Parrish · 781-474-3141 · c.parrish@northeastern.edu

Study contacts (from the official record)

  • Corinna Parrish · 781-474-3141 · c.parrish@northeastern.edu
Multimodal Musical Stimulation for Healthy Neurocognitive Aging (NCT06229093) | Bored Studies