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Multivitamin and Mineral Supplementation and Healthy Aging

University of California, San Diego · with HALEON · NCT07642869

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 40–60 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
150
US sites recruiting
1
Study start
September 5, 2025
Record last updated
June 15, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this study is to determine the impact of MVM supplementation on clinical and biochemical markers associated with healthy aging, with a particular focus on mitochondrial function and metabolism. Specifically, changes in mitochondrial respiration using isolated blood cells will be measured. This method has been used to compare with various other age-related markers of health such as physical function, gait speed, and resting metabolic rate. It is hypothesize that MVM supplementation will impact the function of blood cells. MVM supplementation impacts other markers of health, including serum nutrient levels, metabolomic profiles, physical function, and skeletal muscle composition and quality will be explored. These comprehensive assessments will provide insights into the potential benefits of MVM supplementation for healthy aging and address critical gaps in our understanding of its immediate effects. Further, this study will aid in the understanding of how multivitamin supplements can support heathy aging in mid-life adults, a key time to start including wellness programs in people's lives.

The study cohort will consist of 150 sedentary men and women aged 40-60-years of age. A double-blind, three-arm, placebo-controlled randomized clinical trial will be conducted. Participants will receive a daily oral tablet containing one of two possible formulations of vitamins and minerals or a placebo. The three groups will be MVM "GOLD" blend formula, the US Restage MVM "US CORE", and the placebo group.

Being studied: MVM Core Blend; MVM Gold Blend; Placebo

Conditions: Healthy Aging; Multivitamin and Mineral Supplementation

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • IPAQ-SF categorical score of low or moderate physical activity (indicating sedentary lifestyle).
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Between 40-60 years of age
  • BMI ≥18.5 and ≤32 kg/m2
  • Weight stable for the prior 6 weeks

Exclusion Criteria

  • Is pregnant or nursing.
  • Current smoker.
  • Diabetes (FPG > 180 mg/dL or A1c>8)
  • Heart or cardiovascular condition, including coronary artery disease, congestive heart failure, diagnosed abnormality of heart rhythm, atrial fibrillation and/or a history of myocardial infarction
  • Cancer or history of cancer within the past 5 years
  • Sensory or physical impairment that would prevent participation
  • Parkinson's disease, multiple sclerosis or other neurological condition, including a previous stroke, that may be causing impaired muscle function or mobility
  • Consistent use of any multivitamin and mineral supplement use, or any supplement that may interfere with measurements or biological outcomes (including but not limited to: NAD+ supplements, MitoQ)
  • Individuals with drug interactions as determined by the study physician

Recruiting US locations

  • University of California, San Diego

    La Jolla, CA 92093

    Site contact: Lina Scandalis, PhD · 18588226443 · Lscandalis@health.ucsd.edu

Study contacts (from the official record)

  • Lina Scandalis, PhD · 18588226443 · Lscandalis@health.ucsd.edu
  • David Wing, PhD · 8585349317 · dwing@health.ucsd.edu
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Multivitamin and Mineral Supplementation and Healthy Aging (NCT07642869) | Bored Studies