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Optimizing Liver MRI Using Breath-Holding With and Without Oxygen

University of California, San Francisco · NCT07135401

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–75 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
10
US sites recruiting
1
Study start
December 1, 2025
Record last updated
April 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy adults, ages 18-75.

The main questions it aims to answer are

  • Does breath-holding at end-expiration improve image quality in abdominal MRI scans?
  • Does adding oxygen while breath-holding further reduce motion artifacts in abdominal MRI scans?

Researchers will compare breath-holding with and without oxygen to see if using oxygen improves image quality during MRI scans.

Participants will

  • Be pre-screened for MRI safety and trained on breath-hold procedures
  • Have one non-contrast abdominal MRI scan at the University of California San Francisco (UCSF) China Basin Imaging Center
  • Use two different breath-holding techniques during the scan, with and without oxygen
  • Complete one study visit lasting about 45 minutes to 1 hour

Being studied: Breath-hold conditions

Conditions: MRI; MRI Image Enhancement

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Subject must be within 18-75 years of age;
  • Subject must be able to hear and understand instructions without assistive devices;
  • Subject must provide written informed consent;
  • Subject has the necessary mental capacity to understand instructions, and is able to comply with protocol requirements;
  • Subject is able to remain still for duration of imaging procedure (approximately 30-45 minutes)

Exclusion Criteria

  • Subjects with a weight greater than 499 lbs;
  • Subjects that have metallic/conductive or electrically/magnetically active implants without Magnetic Resonance (MR) Safe or Magnetic Resonance (MR) Conditional labeling, with the exception of dental devices/fillings, surgical clips, and surgical staples determined to be safe for MRI scanning by a physician investigator;
  • Subjects that have implants with MR Unsafe labeling;
  • Subjects that have implants labeled as MR Conditional by the manufacturer for which the allowable conditions are not expected to be achieved by the MR environment or scan protocol;
  • Subjects who have a contraindication to MRI per the screening policy of the participating site;
  • Subjects with any respiratory or cardiovascular condition that could compromise safe breath holding;
  • Subjects who are female and pregnant

Recruiting US locations

  • University of California, San Francisco

    San Francisco, CA 94143

    Site contact: Holland Stacey Stacey · 415-420-5100 · holland.stacey@ucsf.edu

Study contacts (from the official record)

  • John P Roberts, MD · 415-353-3677 · John.Roberts@ucsf.edu
All healthy volunteers studies in California →
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen (NCT07135401) | Bored Studies