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Oropharyngeal Candidiasis (OPC) and S-ECC

Temple University · with Children's Hospital of Philadelphia · NCT05761197

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 10 mo–1 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
70
US sites recruiting
1
Study start
September 1, 2024
Record last updated
June 22, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of severe early childhood caries (S-ECC).

Conditions: Candida Infection; Oral Thrush; Early Childhood Caries

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Male or female individuals at the age of 9-15-month-old
  • Must have at least one fully erupted tooth at baseline visit
  • Parent/guardian willing and able to provide informed consent
  • With or without a history of OPC (the study team will enroll 35 participants with and 35 participants without a history of OPC)

Exclusion Criteria

  • Presence of a systemic medical condition (e.g. Down syndrome etc.)
  • Presence of an orofacial deformity
  • Presence of dental caries
  • Use of systemic antimicrobial therapy within 30 days of the baseline visit
  • Presence of any condition which, in the opinion of the investigator, makes participation in the project not in the individual's best interest.

Recruiting US locations

  • Temple University

    Philadelphia, PA 19140

    Site contact: Yuan Liu, DDS, MS, PhD · 215-707-8029 · ksodtres@temple.edu

Study contacts (from the official record)

  • Yuan Liu, DDS, MS, PhD · 215-707-8029 · yuan.liu0008@temple.edu
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Oropharyngeal Candidiasis (OPC) and S-ECC (NCT05761197) | Bored Studies