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Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

University of Florida · NCT05277025

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–70 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
150
US sites recruiting
1
Study start
March 22, 2022
Record last updated
August 19, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.

Conditions: Fibromyalgia; Rheumatoid Arthritis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Ages 18-70
  • Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM
  • Fulfills the 2010 ACR-EULAR classification criteria for RA
  • Healthy volunteers: No significant pain/fatigue/depression/anxiety.

Exclusion Criteria

  • Diabetes
  • Cancer
  • Advanced liver, kidney or cardiovascular disease
  • Neuropathic pain

Recruiting US locations

  • University of Florida

    Gainesville, FL 32610

    Site contact: Melyssa Godfrey · 352-265-8901 · Melyssa.Godfrey@medicine.ufl.edu

Study contacts (from the official record)

  • Roland Staud, M.D. · 352-294-8200 · staudr@ufl.edu
  • Melyssa M Godfrey, BS · 352-265-8901 · melyssa.m.g@ufl.edu
All arthritis studies in Florida →
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain… (NCT05277025) | Bored Studies