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Parathyroid Tumor Clonal Status

Washington University School of Medicine · NCT05997810

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–80 · Women only
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
839
US sites recruiting
1
Study start
July 28, 2023
Record last updated
May 12, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

To define the frequency of monoclonal-X and polyclonal-X tumors in hyperparathyroid disorders patients having PTX and to define the relationship between parathyroid tumor clonal status and multiple gland neoplasia (MGN), we will compare surgical and pathologic outcomes to tumor clonal status in a multicenter cohort of patients having bilateral neck exploration (BNE) and PTX (primary objectives).

Conditions: Parathyroid Tumor; Primary Hyperparathyroidism; Secondary Hyperparathyroidism (SHPT); Tertiary Hyperparathyroidism

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • 1. Diagnosed with hyperparathyroidism (primary, secondary, or tertiary), biochemically confirmed (e.g., serum calcium and/or intact PTH consistent with the underlying etiology), and undergoing clinically indicated management
  • Female and male patients
  • Age ≥ 18 years
  • Ability to understand and willingness to sign an IRB approved written informed consent document (or that of legally authorized representative, if applicable).

Exclusion Criteria

  • Patients with a history of cervicofacial irradiation.
  • Patients currently taking lithium or with a history of lithium use.
  • Pregnant patients

Recruiting US locations

  • Washington University School of Medicine

    St Louis, MO 63110

    Site contact: Bryan Bear · 314-651-9717 · bearb@wustl.edu

Study contacts (from the official record)

  • John A Olson, MD · (314) 362-8020 · jaolsol@wustl.edu
  • Kathleen Harris · (314) 273-1433 · harrisk@wustl.edu
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Parathyroid Tumor Clonal Status (NCT05997810) | Bored Studies