PET/MRI/EEG Imaging Study in Epilepsy
Massachusetts General Hospital · NCT06974305
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Observational
- Target enrollment
- 30
- US sites recruiting
- 1
- Study start
- September 21, 2023
- Record last updated
- April 23, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
This study aims to better understand how epilepsy alters brain function through neuroimaging of healthy people and people with epilepsy. The study investigates how changes in brain metabolism (sugar consumption, measured by positron emission tomography [FDG-PET], and blood flow, measured by functional magnetic resonance imaging [fMRI]) relate to abnormal interictal electrical activity associated with epilepsy (measured by electroencephalography [EEG]). The study will also compare how the three imaging modalities localize regions of abnormal function in the brain.
Being studied: FDG-PET/fMRI/EEG imaging
Conditions: Epilepsy
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Age 18 or older
Additional Inclusion Criteria for Subjects with Epilepsy:
- Diagnosed with epilepsy with abnormal interictal EEG
Exclusion Criteria
- Contraindications to PET, MRI, or EEG imaging
- History of severe brain disease such as stroke and head trauma
- History of brain surgery
- History of type I or II diabetes mellitus
- Fasting plasma glucose level >200 mg/dL
- Employed under direct supervision of the PI conducting the research
Additional Exclusion Criteria for Healthy Subjects:
- Current use of drugs that modulate brain function
- Current or past history of major medical, neurological, or psychiatric conditions
Recruiting US locations
Athinoula A. Martinos Center
Charlestown, MA 02129
Site contact: Ciprian Catana
Study contacts (from the official record)
- Magdelena S Allen, BA · 617-724-9232 · mallen27@mgh.harvard.edu
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