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Phosphorylated Tau Levels in Donated Blood

The University of Texas Health Science Center, Houston · with National Institute on Aging (NIA) · NCT07157839

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Any age listed · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
250
US sites recruiting
1
Study start
August 28, 2025
Record last updated
February 11, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Alzheimer's disease (AD) is characterized by the accumulation of tau pathology, and blood-based biomarkers such as phosphorylated tau-217 (pTau217) have been identified as sensitive and specific predictors of AD risk. Recent studies suggest that individuals with elevated pTau217 levels may be at increased risk for developing AD and cognitive dysfunction. This observational study will examine donated human plasma samples to determine whether some units of donated blood contain abnormally elevated pTau217 concentrations. The overarching goal is to evaluate whether transfusion of blood with higher pTau217 may pose risks to recipients and whether such units should be avoided in clinical use.

Conditions: Alzheimer&Amp;#39;s Disease

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • The plasma sample from donators.

Exclusion Criteria

  • None.

Recruiting US locations

  • University of Texas Health Science Center at Houston

    Houston, TX 77030

    Site contact: Zhongcong Xie · 7135006207 · Zhongcong.Xie@uth.tmc.edu

Study contacts (from the official record)

  • Zhongcong Xie, M.D., Ph.D. · 17135006207 · Zhongcong.Xie@uth.tmc.edu
All neurology studies in Texas →
Phosphorylated Tau Levels in Donated Blood (NCT07157839) | Bored Studies