Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery
University of Southern California · NCT06815367
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–30 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 33
- US sites recruiting
- 1
- Study start
- January 15, 2024
- Record last updated
- March 30, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS). Blood flow restriction relies on applying pressurized cuffs to the most proximal portion of the limb. Another form of recovery often relied upon is pneumatic compression. The mechanism by which pneumatic compression works is similar to that of a massage, whereby the device progressively increases the pressure on a portion of the limb before releasing and moving further up the limb.The purpose of this study is determine whether BFR or pneumatic compression can be used to decreased DOMS which may indicate enhanced recovery.
Being studied: Pneumatic Compression; Blood Flow Restriction
Conditions: Delayed Onset Muscle Soreness
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- 18-30 years of age
- Recreationally active population
- Women should be on a form of hormonal contraception.
- No current musculoskeletal injuries or pathologies
- Must answer "yes" to all PAR-Q questions.
Exclusion Criteria
- Individuals that routinely train trail running
- Discomfort when running
- Deep vein thrombosis
- Blood clots
- Cancerous lesions
- Sensory or mental impairment
- Unstable fractures
- Acute pulmonary edema
- Acute thrombophlebitis
- Acute congestive cardiac failure
- Acute infections
- Episodes of pulmonary embolism
- Wounds, lesions, infection, or tumors
- Bone fractures or dislocations
- Increased venous and lymphatic return
- Answers "no" to any of the PAR-Q screening questions
Recruiting US locations
University of Southern California
Los Angeles, CA 90033
Site contact: Bailey McLagan · 323-442-2498
Study contacts (from the official record)
- Bailey McLagan, MS · 323-442-2498 · mclagan@usc.edu
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