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Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat

State University of New York at Buffalo · with United States Department of Defense · NCT06475339

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–39 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
24
US sites recruiting
1
Study start
November 1, 2024
Record last updated
January 26, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The overall goal of this project is to identify a work/rest cycle that allows for faster mission completion needed in emergency situations, compared to current Army heat guidance, while mitigating heat strain and neuromuscular fatigue. This project will determine the trade-off between faster mission completion and risk of heat strain and physical performance decrements. Completion of this project will allow military leaders to make informed decisions by understanding the impact of their choices on the magnitude of physical performance decrements and expected heat casualties, setting up hot weather missions for success.

Being studied: 30/30 work/rest cycle; 30/20 work/rest cycle; 40/30 work/rest cycle; 20/12 work/rest cycle

Conditions: Hyperthermia; Fatigue; Heat

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy individuals
  • Physically active

Exclusion Criteria

  • History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease
  • Hypertensive (systolic blood pressure > 139 mmHg, diastolic blood pressure > 89 mmHg) or tachycardic (heart rate > 100 bpm) during the screening visit
  • Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin)
  • Tobacco or nicotine use currently or in the past six months
  • Musculoskeletal injury expected to impact exercise in the protocol
  • A positive pregnancy test at any point in the study
  • Study physician discretion based on any other medical condition or medication
  • Inability to understand or follow instructions or the protocol
  • Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.

Recruiting US locations

  • Center for Research and Education in Special Environments

    Buffalo, NY 14214

    Site contact: Riana R Pryor, PhD, ATC · 716-829-5456 · RPryor@buffalo.edu

Study contacts (from the official record)

  • Riana R Pryor, PhD · 7168295456 · rpryor@buffalo.edu
All healthy volunteers studies in New York →
Predicting Responses to Exhausting, Prolonged, And Repeated… (NCT06475339) | Bored Studies