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Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

University of Pittsburgh · NCT02994121

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 7+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
7500
US sites recruiting
1
Study start
December 2016
Record last updated
December 29, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.

Conditions: Multiple Sclerosis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Inclusion criteria for MS patients include:
  • Age 7 years or older
  • Willing and able to provide consent (for >=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
  • Diagnosis of multiple sclerosis or related disorders, including a first central nervous system demyelinating episode with a positive MRI scan or abnormal MRI scans characteristic of MS but no clinical symptoms of the disease
  • For healthy controls:
  • Age 7 years or older
  • Willing and able to provide consent (for >=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
  • No known personal history of multiple sclerosis or related disorders
  • No other chronic diseases
  • Family members, unrelated household controls, or controls from the general population could be eligible

There is no exclusion criteria.

Recruiting US locations

  • University of Pittsburgh

    Pittsburgh, PA 15260

    Site contact: Zongqi Xia, MD, PhD · 412-383-5377

Study contacts (from the official record)

  • Zongqi Xia, MD, PhD · 412-383-5377 · msstudy2@pitt.edu
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Prospective Investigation of Multiple Sclerosis in the Three… (NCT02994121) | Bored Studies