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Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

Oregon Health and Science University · with National Eye Institute (NEI) · NCT07065747

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 5–85 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
125
US sites recruiting
1
Study start
September 1, 2024
Record last updated
July 17, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.

Conditions: Anterior Uveitis (AU); Birdshot Chorioretinitis; Behcet Disease; Herpes Simplex Virus; Juvenile Idiopathic Arthritis (JIA); Spondyloarthritis (SA); Sarcoidosis; Posterior Vitreous Detachment

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, Juvenile Idiopathic Arthritis (JIA) associated chronic anterior uveitis, Herpes Simplex Virus (HSV) anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade.
  • Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD).
  • Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery.

Exclusion Criteria

  • Inability to give informed consent.
  • Inability to maintain stable fixation for OCT imaging.
  • Inability to commit to required visits to complete the study.
  • Pregnancy and breastfeeding.

Recruiting US locations

  • Casey Eye Institute - Oregon Health & Science University

    Portland, OR 97239

Study contacts (from the official record)

  • Humberto Martinez, COT, MBA · 503-494-7712 · martinhu@ohsu.edu
  • Denzil Romfh, OD · 503-494-4351 · romfhd@ohsu.edu
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Quantification & Classification of Inflammatory Cells in Uveitis… (NCT07065747) | Bored Studies