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Recovery of Physical Function After Critical Illness In Older Adults

University of Kentucky · NCT07225257

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–99 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
150
US sites recruiting
1
Study start
March 11, 2026
Record last updated
May 28, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The proposed study is a prospective, observational study assessing the recovery of muscle and physical function in patients surviving critical illness (n =150) at hospital discharge (baseline) and repeated serially. Patients will be enrolled after life-saving modalities have been weaned near hospital discharge. Patients will participate in testing at baseline, 3-, 6-, 12-, and 24-months after hospital discharge. In a subset of patients (n = 18), muscle biopsies will be performed at baseline and then repeated once at either 12- or 24-months after hospital discharge.

Conditions: Sepsis; Acute Lung Injury(ALI)

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • adult patients (≥40 years of age)
  • patients who have survived an ICU admission of at least 72 hours
  • diagnosis of acute lung injury or sepsis are eligible.

Exclusion Criteria

  • individuals who were not ambulatory prior to ICU admission,
  • not expected to survive at least 6 months,
  • have a new or pre-existing brain infarct, injury, or neurological condition with deficits preventing participation in physical testing,
  • have a pre-existing geriatric syndrome that were confound recovery trajectory

Recruiting US locations

  • University of Kentucky, Lexington, Kentucky 40536

    Lexington, KY 40536

    Site contact: Doug A Long, MS · 8593231100 · delong2@uky.edu

Study contacts (from the official record)

  • Doug Long, MS · 859-218-0596 · delong2@uky.edu
  • Kirby P Mayer, DPT, Ph.D. · 859-218-0596 · kpmaye2@uky.edu
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Recovery of Physical Function After Critical Illness In Older Adults (NCT07225257) | Bored Studies