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Bored Studies

This study is not recruiting (status: Active, not recruiting).

It is no longer listed as an open opportunity. The official record is linked below for reference. Find recruiting studies.

Active, not recruitingAccepts healthy volunteers

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)

Dana-Farber Cancer Institute · with Breast Cancer Research Foundation · NCT06322888

Key facts

Compensation
Not listed in the record
Who can join
18 Years to 59 Years · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
46
US sites recruiting
2
Study start
March 28, 2024
Record last updated
October 26, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this study is to learn more about how exercise might lower the risk of developing breast cancer in women with dense breast tissue by studying changes that occur in breast tissue and blood as a result of participating in an exercise program.

The names of the study groups in this study are:

  • Exercise Training Group
  • Waitlist Control Group

Being studied: Exercise Training Program

Conditions: Breast Cancer; Breast Cancer Female

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Women aged 18-59
  • Heterogeneously dense/extremely dense (BIRADS 3 or 4) breast tissue on mammogram within the past 12 months
  • Physically inactive; engaging in \<60 minutes of moderate or vigorous intensity exercise per week, as assessed by Godin Leisure Time screener
  • Not pregnant or breastfeeding
  • English speaking and able to read English. Investigators are only enrolling English-speaking participants to this study at this time due to the fact that investigators currently only have English-speaking exercise trainers with the proper qualifications to conduct the exercise training
  • Written informed consent prior to any study-related procedures

Exclusion Criteria

  • Self-reported inability to walk 2 blocks (at any pace)
  • Prior history of breast cancer; prior DCIS is allowable as long as participant is not taking endocrine therapy and has at least 1 breast that has not been irradiated
  • On oral or implantable hormonal contraceptives, postmenopausal hormone replacement therapy, a selective estrogen receptor modulator or an aromatase inhibitor; Mirena or other IUD is acceptable
  • Consistent strength training in the past 3 months
  • Use of weightloss drugs
  • Cardiovascular, respiratory or musculoskeletal disease or joint problems that preclude moderate exercise. Examples would include unstable angina, recent myocardial infarction, oxygen-dependent pulmonary disease, and osteoarthritis requiring imminent joint replacement. Moderate arthritis that does not preclude physical activity is not a reason for ineligibility
  • Psychiatric disorders or conditions that would preclude participation in the study intervention (e.g. untreated major depression or psychosis, substance abuse, severe personality disorder)

Recruiting US locations

Resistance and Aerobic Exercise for Prevention in Women With Dense… (NCT06322888) | Bored Studies