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Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor

University of Alabama at Birmingham · NCT04954664

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–99 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
44
US sites recruiting
1
Study start
August 11, 2021
Record last updated
December 29, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor called Recombinant Human Platelet-Derived Growth Factor (rhPDGF).

Being studied: Allograft particles hydrated with rhPDGF; Allograft particles hydrated in a conventional way with saline.

Conditions: Dental Implant; Bone Loss

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • English speaking
  • At least 18 years old
  • Must be a patient of the UAB Dental School
  • Able to read and understand informed consent document
  • Need for implants to replace missing tooth or teeth in at least one quadrant of the mouth.
  • Insufficient alveolar ridge width for endosseous implant placement defined as 5mm or less as determined by bone sounding and cone beam computed tomography (CBCT) scan.

Exclusion Criteria

  • Non-English speaking
  • Less than 18 years old
  • Smokers/tobacco users (>10 cigarettes/day)
  • Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
  • Patient is a poor compliance risk (i.e., poor oral hygiene, history of alcohol or drug abuse)
  • Vertical loss of bone at edentulous ridge.

Recruiting US locations

  • Unversity of Alabama at Birmingham, School of Dentistry

    Birmingham, AL 35294-0007

    Site contact: Hussein Basma, DDS, MS · 205-975-2888 · basma86@uab.edu

Study contacts (from the official record)

  • Hussein Basma, DDS, MS · 205-934-2888 · basma86@uab.edu
  • Sarah Startley, DMD · 205-975-8711 · ss1971@uab.edu
All healthy volunteers studies in Alabama →
Ridge Augmentation Using Allograft Particles Hydrated With or… (NCT04954664) | Bored Studies