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Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer

City of Hope Medical Center · with National Cancer Institute (NCI) · NCT06408220

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 40–80 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
240
US sites recruiting
1
Study start
June 27, 2024
Record last updated
March 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This clinical trial evaluates the usefulness of various risk assessment tests, including Helicobacter pylori (H. pylori) breath testing, questionnaires, and endoscopies for identifying participants at high risk for stomach cancer. H. pylori is a bacteria that causes stomach inflammation and ulcers in the stomach. People with H. pylori infections may be more likely to develop cancer in the stomach. H. pylori breath testing can help identify the presence of H. pylori infection in a participant and help identify if the participant may be at a higher risk of developing stomach cancer. An endoscopy uses a thin, flexible lighted tube that is inserted inside the esophagus, stomach, and first part of the small intestine. This allows the doctor to see and look for abnormal areas that may need to be biopsied. Risk assessment including H. pylori evaluation, questionnaires, and endoscopies may help identify participants at high risk for stomach cancer and may be a useful screening tool for earlier stomach cancer diagnosis.

Being studied: Biopsy; Biospecimen Collection; Breath Test; Esophagogastroduodenoscopy; Questionnaire Administration

Conditions: Gastric Carcinoma

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Documented informed consent of the participant and/or legally authorized representative
  • Assent, when appropriate, will be obtained per institutional guidelines
  • Age: ≥ 40 years to ≤ 80 years
  • Identify as a racial minority either Asian, Hispanic, or Black American
  • Willingness to:
  • Provide blood samples and undergo upper endoscopy

Exclusion Criteria

  • Identify as Non-Hispanic White
  • History of gastric cancer
  • Known premalignant lesions of the stomach
  • History of upper endoscopy within 2 years
  • Women of childbearing potential: Pregnant/ nursing
  • An employee who is under the direct/indirect supervision of the principal investigator (PI)/a coinvestigator/the study manager
  • A direct study team member

Recruiting US locations

  • City of Hope Medical Center

    Duarte, CA 91010

    Site contact: Yanghee Woo · 626-218-0220 · yhwoo@coh.org

Risk Assessment Evaluation for Identifying Participants at High… (NCT06408220) | Bored Studies