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Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Bettina Mittendorfer · NCT07083557

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–100 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
100
US sites recruiting
1
Study start
January 1, 2027
Record last updated
May 7, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases, nutrition, and metabolism (the process by which a substance is handled in the body) at the University of Missouri. As technology changes and uses new testing methods, it is necessary to compare results from old tests, equipment and devices and new tests, equipment, or devices and the reproducibility of these measurements to make sure the results are accurate. Reproducibility means performing the same test more than once to see if the same results can be achieved each time. This study will look at the validation and reproducibility of tests and laboratory assays in participants who are healthy or affected by relevant endocrine, cardiometabolic, and musculoskeletal disorders.

Being studied: Endothelial cell collection

Conditions: Obesity and Obesity-related Medical Conditions; Diabetes; Atherosclerotic Disease; Heart Failure; MASH; Sarcopenia; Osteoporosis; Hyperparathyroidism; Hypoparathyroidism; Ischemic Heart Disease; Cystic Fibrosis (CF); Chronic Kidney Disease(CKD); Osteopenia; Cachexia

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • ≥18 and ≤100 years of age
  • body mass index ≥16.0 and ≤60 kg/m2

Exclusion Criteria

  • \<18 and >100 years of age
  • body mass index \<16.0 or >60 kg/m2
  • allergies, intolerances, or dietary restrictions to meal ingredients, vegans or vegetarians
  • use of medications or dietary supplements (e.g., anti-inflammatories, immune modulators, etc) that could interfere with the particular assay/techniques being evaluated
  • engaged in regular structured exercise >150 min per week unless needed for validation of the assay/technique being evaluated
  • significant organ system dysfunction or diseases, except those that are sought for validation of the assay/technique being evaluated
  • alcohol use disorder as defined by the National Institute of Alcohol Abuse and Alcoholism or use of controlled substances unless alcohol use disorder is required for validation of the assay/technique being evaluated
  • pregnant women, persons who smoke, prisoners, and inability to grant voluntary informed consent.

Recruiting US locations

  • University of Missouri-Columbia

    Columbia, MO 65211

    Site contact: Study coordinator · 573-884-6852 · ahmc4@health.missouri.edu

Study contacts (from the official record)

  • Study coordinator · 573-884-6852 · ahmc4@health.missouri.edu
All weight loss studies in Missouri →
Routine Validation and Reproducibility Testing of Laboratory… (NCT07083557) | Bored Studies