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School Inner City Air Study

Massachusetts General Hospital · with Boston Children's Hospital, National Institute of Allergy and Infectious Diseases (NIAID) · NCT05953233

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 6–90 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
200
US sites recruiting
1
Study start
September 15, 2024
Record last updated
December 11, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this randomized clinical trial is to test the efficacy of high efficiency particulate air (HEPA) cleaners in reducing respiratory viral exposure and infections in elementary school classrooms. Classrooms will be randomized to active vs. sham HEPA cleaners. The main questions it aims to answer are:

  • Do classroom HEPA cleaners reduce exposure to viruses?
  • Do classroom HEPA cleaners reduce student and teacher infections?
  • Do classroom HEPA cleaners reduce infections in family members?

Being studied: Active classroom HEPA cleaner; Sham classroom HEPA cleaner

Conditions: Viral Infection

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

Children

  • Grades K-5 (age 6-12 years)
  • Attend one of the schools that the study team has permission to obtain classroom/school environmental samples
  • Have no plans to move schools within the upcoming 12 months
  • Subject and/or parent guardian must be able to understand and provide informed consent and also willing to participate in the study

Adults

  • Adult (age 21 or older) parent, caretaker, or household member of child participating in this study, or teacher in classroom participating in study
  • Able to understand and provide informed consent

Exclusion Criteria

Children

  • Contraindication to or inability to participate in home self-collection of nasal swab samples
  • Severe chronic diseases (e.g. cancer, genetic or congenital disorders interfering with mobility)
  • Severe neurobehavioral, neurodevelopmental or psychiatric disorders requiring special assistance
  • Families who do not speak English or Spanish well enough to complete the survey questions, as validated versions in other languages are not available for all of the measures

Adults

  • Contraindication to or inability to participate in home self-collection of nasal swab samples
  • Severe chronic diseases (e.g. cancer, genetic or congenital disorders interfering with mobility)
  • Severe neurobehavioral, neurodevelopmental or psychiatric disorders requiring special assistance
  • Families who do not speak English or Spanish well enough to complete the survey questions, as validated versions in other languages are not available for all of the measures

Recruiting US locations

  • Mass General Brigham

    Boston, MA 02114

    Site contact: Peggy Lai, MD MPH

Study contacts (from the official record)

  • Peggy Lai, MD MPH · 617-875-9878 · plai@mgh.harvard.edu
  • Wanda Phipatanakul, MD MS · 857-218-5336 · wanda.phipatanakul@childrens.harvard.edu
All healthy volunteers studies in Massachusetts →
School Inner City Air Study (NCT05953233) | Bored Studies