Social Determinants and a Diabetes Prevention Program Tailored for African Americans
University of Missouri, Kansas City · with University of Massachusetts, Amherst, University of Kansas · NCT05301413
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Phase 2
- Target enrollment
- 360
- US sites recruiting
- 1
- Study start
- July 20, 2022
- Record last updated
- May 25, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
African Americans (AAs) have rates of diabetes mellitus (DM) twice that of Whites and are disproportionately affected by leading risk factors for DM - obesity and low-income. A critical strategy in the battle against DM is the Diabetes Prevention Program (DPP), an evidence-based intervention that significantly delays or prevents Type 2 diabetes through the promotion of diet change, exercise and modest weight loss. However, weight loss from the DPP among AAs is about half that of White participants, and suboptimal AA attendance is a critical contributor. The investigators propose to conduct a study that will address social determinants (SD) that challenge DPP attendance with underserved African Americans from a safety net hospital. The investigators will examine DPP attendance and weight loss with participants randomized to 3 groups: standard DPP, a culturally-tailored DPP to address acceptability, and a culturally-tailored DPP enhanced to address socioeconomic-related barriers to DPP participation. This novel study is the first to tailor the DPP to address SD cultural and socioeconomic barriers that limit DPP attendance and reduce its effectiveness on outcomes. The proposed multidimensional, SD tailored DPP has great potential to be a feasible and scalable model to reduce DM risks among urban, African Americans and ultimately reduce DM disparities.
Being studied: Culturally Tailored Diabetes Prevention Program; Culturally Tailored DPP Enhanced with Socioeconomic Supports; Diabetes Prevention Program
Conditions: PreDiabetes; Overweight and Obesity
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Black/African American
- Overweight ([BMI> 24); and
- Diagnosed with prediabetes OR pre-diagnosed with gestational diabetes OR high risk result on prediabetes risk test
Exclusion Criteria
- Diagnosed with diabetes
- Pregnant
- Not fluent in English
- Currently pregnant, planning a pregnancy in the next year, currently breastfeeding or have given birth in the last 6 months
- Currently participating in a weight loss program
- Currently have a medical condition that causes drastic weight loss
- Bariatric weight loss surgery in last year
- Cannot walk a 1-block distance without assistance and without stopping due to pain, tightness, or pressure in the chest
- Had heart failure
- Not willing to use a fitness tracker, wi-fi scale, and the internet
- Not available in the evening one day each week to participate in a class
Recruiting US locations
University of Missouri-Kansas City
Kansas City, MO 64108
Site contact: Jannette Berkley-Patton, PhD · 816-235-6362
Study contacts (from the official record)
- Christopher Winders · 18162355370 · windersc@umkc.edu
- Carole Bowe Thompson · 8162356062 · bowethompsonc@umkc.edu
Similar studies in Missouri
All weight loss studies in Missouri →- RecruitingHealthy volunteersOvernight stay mentioned
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity
Bettina Mittendorfer
- Location
- Columbia, MO
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersOvernight stay mentioned
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)
Bettina Mittendorfer
- Location
- Columbia, MO
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersEarly Phase 1
Sex Disparities in Hypoxic Vasodilation and Impact of Obesity
University of Missouri-Columbia
- Location
- Columbia, MO
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Chesterfield, MO + 55 other US sites
- Eligibility basics
- Ages 18–79