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Social Functioning in Opioid Use Disorder

Medical University of South Carolina · with National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) · NCT07044466

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
230
US sites recruiting
1
Study start
August 13, 2026
Record last updated
August 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Problems with social functioning are core to opioid use disorder (OUD), though specific, modifiable social functioning targets and how they relate to OUD treatment outcomes are poorly understood. This study will utilize both data from both patients with OUD and their concerned significant other (CSO) to examine associations between specific social functioning metrics and OUD treatment outcomes. Findings from this study will inform future precision-medicine approaches for people with OUD, a population in significant need of enhanced treatment approaches to combat opioid morbidity and mortality.

Being studied: CBT4CBT-Buprenorphine

Conditions: Opioid Use Disorder

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Any sex or gender; any race or ethnicity; aged 18 years or older
  • Patient participants must meet DSM-5 diagnostic criteria for current (i.e., past 12 months) OUD (assessed via the Quick Structured Clinical Interview for DSM-5; Quick SCID)
  • Patient participants must be on medication for opioid use disorder (MOUD), as prescribed by their provider, for no more than 12 weeks prior to study initiation
  • Patient participants must be in treatment at a clinic in South Carolina
  • Concurrent substance use disorders (e.g., alcohol, cannabis) for the patient participant are acceptable, provided opioids are the patient participant's primary substance of choice
  • Patient participants must identify a CSO participant who consents to participation in the study as well

Exclusion Criteria

  • Moderate-to-severe opioid withdrawal as defined by a score of ≥21 on the Subjective Opioid Withdrawal Scale
  • Meeting DSM-5 criteria for a history of or current psychotic or bipolar disorders
  • Current suicidal or homicidal ideation and intent; participants who present a serious suicide risk are likely to require hospitalization during the study and they will be referred clinically
  • CSO participants meeting DSM-5 criteria for opioid use disorder or any other substance use disorder, excepting tobacco use disorder, mild cannabis use disorder, and mild alcohol use disorder
  • Severe interpersonal violence in the past six months between the patient and the CSO, as defined by an adapted version of the Conflict Tactics Scaled Revised (CTS-2)
  • Pregnancy for patient participants
  • Prisoners, institutional individuals, and children will not be recruited for this study.

Recruiting US locations

  • Medical University of South Carolina

    Charleston, SC 29412

    Site contact: Amber Jarnecke, PhD · 843-876-3115 · jarnecka@musc.edu

Study contacts (from the official record)

  • Amber Anderson, BA · 843-876-3115 · anderamb@musc.edu
  • Kevin Branson, MA · 843-876-3115 · bransonk@musc.edu
All healthy volunteers studies in South Carolina →
Social Functioning in Opioid Use Disorder (NCT07044466) | Bored Studies