Skip to content
Bored Studies
RecruitingAccepts healthy volunteers

Sodium in the Skin and Atopic Dermatitis

University of California, San Francisco · with National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · NCT06998446

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 50+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
90
US sites recruiting
2
Study start
May 12, 2025
Record last updated
July 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this observational study is to understand factors associated with skin sodium storage in healthy adults and people with atopic dermatitis ages 50 and above.

The study is designed to test whether diet and skin barrier function are associated with skin sodium concentration and whether skin sodium concentration is linked to atopic dermatitis and immune profiles over time.

Participants will be asked to complete questionnaires, provide bio samples, and undergo non-contrast sodium MRI at 2-3 time points over 3-24 months.

Conditions: Eczema; Atopic Dermatitis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Ages 50 years and above
  • Willing to undergo non-contrast MRI (e.g., no contraindications to MRI, such as cardiac pacemakers, non-compatible intracranial vascular clips or pregnancy).

Exclusion Criteria

  • History of autoimmune disease.
  • Cardiac events in the last six months.
  • Impaired function of the liver or kidneys (glomerular filtration rate \<60ml/min).
  • Current use of medications that influence sodium excretion (e.g. thiazide diuretics, SGLT2 inhibitors and spironolactone), and/or chemotherapy or antibiotic treatment.
  • Currently receiving phototherapy or taking systemic medications for atopic dermatitis including cyclosporine, methotrexate, or other broad immunosuppressive medications.

(Patients on dupilumab will not be excluded if they have been on dupilumab for at least two months and still meet the criteria for severe disease.)

Recruiting US locations

  • San Francisco VA Medical Center

    San Francisco, CA 94115

    Site contact: Frank Asare-Bediako, BS · 520-304-8529 · frank.asarebediako@ucsf.edu

  • UCSF Mt Zion Campus

    San Francisco, CA 94511

    Site contact: Jie Zhu, MD · 415-502-0433 · Jie.Zhu2@ucsf.edu

Study contacts (from the official record)

  • Jie Zhu, MD · 415-502-0433 · Jie.Zhu2@ucsf.edu
  • Katrina Abuabara, MD · 415-514-9769 · katrina.abuabara@ucsf.edu
All dermatology studies in California →
Sodium in the Skin and Atopic Dermatitis (NCT06998446) | Bored Studies