Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain
The University of Texas Health Science Center, Houston · with National Institute of Neurological Disorders and Stroke (NINDS) · NCT06968689
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–60 · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 60
- US sites recruiting
- 1
- Study start
- June 1, 2025
- Record last updated
- March 2, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Transcranial Alternating Current Stimulation (tACS), sham and Transcranial random noise stimulation (tRNS)
Being studied: transcranial alternating current stimulation (tACS); Sham; transcranial random noise stimulation (tRNS)
Conditions: Pain
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Meet the MRI / EEG screening criteria
- Fluent in English
Exclusion Criteria
- Current or history of major medical, neurological, or psychiatric illness based on self-report
- History of cardiac, respiratory, or nervous system disease that, in the investigator's judgment, precludes participation in the study because of a heightened potential for adverse outcome (for example: asthma or claustrophobia)
- History of head trauma
- Pregnant or lactating
- Presence of any contraindications to MRI scanning (for example: cardiac pacemaker, metal implants, claustrophobia, pregnancy, cannot lie still in fMRI scanner)
- Conditions making study participation difficult (e.g., paralysis, psychoses, or other severe psychological problems as per the judgment of a study investigator during Session 1)
- Active substance abuse disorders (based on subject self-report)
Recruiting US locations
The University of Texas Health Science Center at Houston
Houston, TX 77030
Site contact: Wen Li, PhD · (713) 486-2700 · Wen.Li.1@uth.tmc.edu
Study contacts (from the official record)
- Wen Li, PhD · (713) 486-2700 · Wen.Li.1@uth.tmc.edu
- Jada Malveaux · (713) 486-2700 · Jada.Malveaux@uth.tmc.edu
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