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Study of Low-intensity Focused Ultrasound Effects on Heat Evoked fMRI Signals

Virginia Polytechnic Institute and State University · NCT05303415

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–65 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
80
US sites recruiting
1
Study start
May 6, 2022
Record last updated
June 8, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Study of LIFU on fMRI pain signals. Participants receive low-intensity focused ultrasound (LIFU) and fMRI scans to measure changes in both resting and heat pain signals. Physiology may also be measured. Questionnaires and symptom monitoring will take place. The study takes place over 4 study visits.

Being studied: Neuromodulation with low-intensity focused ultrasound

Conditions: Pain

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Healthy volunteers, all ethnicities, who understand and speak English.

Exclusion Criteria

Claustrophobia (scanning environment may be uncomfortable). Contraindications to MRI: including pacemaker, aneurysm clips, neurostimulators, cochlear implants, metal in eyes, steel worker, or other implants.

Contraindications to CT: pregnancy Active medical disorder or treatment with potential CNS effects (e.g. Alzheimer's) History of neurologic disorder. (e.g. Parkinson's, Epilepsy, or Essential Tremor) History of head injury resulting in loss of consciousness for >10 minutes. History of alcohol or drug dependence (through self-report).

Recruiting US locations

  • Fralin Biomedical Research Institute

    Roanoke, VA 24016

    Site contact: Jessica Florig, MPH · 5405262375 · legonlab@vtc.vt.edu

Study contacts (from the official record)

  • Jessica W Florig, MPH · 540-526-2261 · legonlab@vtc.vt.edu
All healthy volunteers studies in Virginia →
Study of Low-intensity Focused Ultrasound Effects on Heat Evoked… (NCT05303415) | Bored Studies