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The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

University of California, Davis · NCT06476795

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 45–70 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
5
US sites recruiting
1
Study start
June 1, 2024
Record last updated
August 7, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Recently a dietary recommendation of 400 - 600 mg/ day has been proposed for the reduced risk of developing cardiovascular disease. Dietary flavanols can be obtained from the intake of foods such as tea, cocoa, wine, berries and apples. Incorporating Chardonnay Marc (the skins and seeds of Chardonnay grapes) into the diet can be an additional source of dietary flavanols. Like other flavanol-rich foods, Chardonnay Marc provides fiber and polysaccharides that may benefit gut health. This study seeks pilot data on the impact of the daily incorporation of Chardonnay Marc powder into the diet on markers of gut and cardiometabolic health.

Being studied: Chardonnay Marc

Conditions: Cardiovascular Diseases; Adiposity; Cardiometabolic Syndrome

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Postmenopausal female, with a cessation of menses for at least 2 years
  • 45-70 years of age
  • BMI 25- 49.9 kg/m2
  • Fasting triglycerides > 120 mg/dL
  • Subject is willing and able to comply with the study protocols and procedures.

Exclusion Criteria

  • Self-reported use of daily anticoagulation agents including aspirin, NSAIDs
  • Prescription medications and supplements, except for a 6 month stable dose of thyroid medications
  • Vegan, Vegetarians, food faddists or those consuming a non-traditional diet
  • Fruit consumption ≥ 3 cups/day
  • Vegetable consumption ≥ 4 cups/day
  • Coffee/tea ≥ 3 cups/day
  • Dark chocolate ≥ 3 oz/day
  • Self-reported restriction of physical activity due to a chronic health condition
  • Self-reported chronic/routine high intensity exercise
  • Blood pressure ≥ 140/90 mm Hg
  • Self-reported renal or liver disease
  • Self-reported heart disease, which includes cardiovascular events and stroke, diabetes
  • Peripheral artery disease Raynaud's syndrome or disease
  • Inability to properly place or wear the PAT probes or abnormal measurements on pre-screening PAT
  • Self-reported cancer within past 5 years
  • Self-reported gastrointestinal disorders, apart from appendix removal
  • Unwillingness to stop any supplement use, including herbal, plant or botanical, fish oil, oil supplements six weeks prior to study enrollment.
  • Indications of substance or alcohol abuse within the last 3 years
  • All forms of smoking (e.g. vaping, cigarette, cannabis)
  • Current enrollee in a clinical research study.

Recruiting US locations

  • University of California, Davis

    Davis, CA 95616

    Site contact: Roberta Holt, PhD · 530-400-5952 · rrholt@ucdavis.edu

Study contacts (from the official record)

  • Roberta R Holt, PhD · 5304005952 · rrholt@ucdavis.edu
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The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic… (NCT06476795) | Bored Studies