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The ROAR Study: Reactive Oxygen Species and Reproduction

University of California, San Francisco · NCT06831019

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–43 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
1100
US sites recruiting
1
Study start
July 7, 2025
Record last updated
February 17, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This is a prospective cohort study characterizing follicular fluid and serum levels of oxidative stress in women with various infertility diagnoses undergoing in vitro fertilization, and assessing the relationship of oxidative stress to oocyte competence as determined by embryo development outcomes. Furthermore, we will measure oxidative stress in sperm and correlate the overall oxidative stress within the couple with IVF and pregnancy outcomes of the resultant embryos.

Being studied: Oxidative stress markers

Conditions: Ovarian Aging; IVF Outcome; Oxidative Stress

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Female age 18-43 years
  • Subjects planning blastocyst culture for preimplantation genetic screening (PGS) for aneuploidy.
  • Male partners 18 years of age or older.
  • Must be a registered patient at UCSF Center for Reproductive Health
  • Patient and partner must both be physically present on the day of retreival

Exclusion Criteria

  • Female partner age 44 or older
  • Planning fresh transfer (hybrid PGS cycle)
  • Cleavage stage biopsy
  • Planning to use frozen sperm

Recruiting US locations

Study contacts (from the official record)

  • Elena Hoskin, BS · (415) 885-3598 · elena.hoskin@ucsf.edu
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The ROAR Study: Reactive Oxygen Species and Reproduction (NCT06831019) | Bored Studies