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To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.

University of Alabama at Birmingham · NCT07191262

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–85 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
40
US sites recruiting
1
Study start
March 2, 2026
Record last updated
March 20, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and ridge preservation grafting followed by daily use of commercially available an essential oil (EO) mouthrinse and EDTA mouthrinse.

Being studied: 0.12% CHX and Essential Oil mouthrinse; 2.6% EDTA and 0.2% EDTA mouth rinse

Conditions: Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Able to read and provide informed consent in English
  • At least 18 years old
  • Established and registered patient of the UAB School of Dentistry
  • Patients presenting with one single rooted tooth determined to need extraction and simultaneous ridge preservation bone grafting for future dental implant placement.
  • Presence of periodontally healthy, non-carious neighboring teeth and/or healthy restored dental implants on either side of the tooth planned for extraction.
  • No anticipated need for surgical and/or endodontic care at teeth adjacent to the proposed surgical site during the study period.

Exclusion Criteria

  • Non-English speaking
  • Age less than 18 years old or older than 85 years old
  • Smokers/nicotine users (>10 cigarettes or equivalent/day)
  • Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
  • Multiple adjacent teeth require extraction and grafting
  • Absence of adjacent teeth/implants on either side of the tooth to be extracted.
  • Documented or suspected allergy or sensitivity to any study product

Recruiting US locations

  • University of Alabama at Birmingham

    Birmingham, AL 35294-0007

    Site contact: Maria Geisinger, DDS, MS · 205-934-4984 · miagdds@uab.edu

Study contacts (from the official record)

  • Maria L Geisinger, DDS, MS · 205-934-4984 · miagdds@uab.edu
  • Sarah Jane Startley, DMD · 205-975-8711 · ss1971@uab.edu
All healthy volunteers studies in Alabama →
To Compare Post-Extraction Use of a Novel… (NCT07191262) | Bored Studies