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RecruitingAccepts healthy volunteersPhase 2

Tranexamic Acid in Nasal Mohs Reconstruction

Vanderbilt University Medical Center · NCT06057675

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 2
Target enrollment
100
US sites recruiting
1
Study start
March 19, 2024
Record last updated
September 9, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.

Being studied: Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine); Control (1% lidocaine with 1:100,000 epinephrine)

Conditions: Postoperative Bleeding; Skin Cancer Face

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Adults at least 18 years of age undergoing local flap reconstruction (bilobe flap, note flap dorsal nasal flap, advancement flap) of a nasal defect following Mohs micrographic surgery. Reconstructive procedures will be performed by Drs. Yang or Patel in the division of Facial Plastic Surgery in the Department of Otolaryngology, Head and Neck Surgery at Vanderbilt University Medical Center.
  • No other facial plastic procedure or sinus surgery performed simultaneously.
  • Lack of all the below exclusion criteria.

Exclusion Criteria

  • Known allergy to TXA
  • Intracranial bleeding
  • Known defective color vision
  • History of venous or arterial thromboembolism
  • History of coagulation disorder
  • Active thromboembolic disease
  • Severe renal impairment (diagnosis of chronic kidney disease)
  • History of acute myocardial infarction
  • History of stroke
  • History of seizure
  • History of liver failure
  • Preoperative lab results indicating thrombocytopenia (platelets \<150,000), increased bleeding risk (PT over 45, INR over 1.2).

Recruiting US locations

  • Vanderbilt University Medical Center

    Nashville, TN 37232

    Site contact: Connie Ma, MD

Study contacts (from the official record)

  • Connie Ma, MD · 2815366877 · connie.ma@vumc.org
All healthy volunteers studies in Tennessee →
Tranexamic Acid in Nasal Mohs Reconstruction (NCT06057675) | Bored Studies