Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation
Medtronic Cardiovascular · NCT07321899
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Not accepted (a condition is required)
- Study type
- Interventional · Not applicable
- Target enrollment
- 1186
- US sites recruiting
- 13
- Study start
- September 11, 2026
- Record last updated
- September 25, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
This clinical trial evaluates the safety and effectiveness of the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in symptomatic patients with severe or greater tricuspid regurgitation.
Being studied: Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System; Edwards EVOQUE Tricuspid Valve Replacement (TTVR) System
Conditions: Severe Tricuspid Regurgitation
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Age ≥18 years at the time of consent.
- Severe symptomatic tricuspid regurgitation (TR) despite optimal medical therapy (OMT).
- Local site multidisciplinary heart team experienced in tricuspid valve therapies agrees that the subject is appropriate for TTVR.
Exclusion Criteria
- Any tricuspid device currently in place.
- Anatomic contraindications.
- Need for emergent or urgent surgery.
- Left ventricular ejection fraction \<25%.
Recruiting US locations
University of Alabama at Birmingham (UAB) Hospital
Birmingham, AL 35233
Site contact: Kathy Phillips · 205-975-1888 · kcphillips@uabmc.edu
Abrazo Arizona Heart Hospital
Phoenix, AZ 85016
Site contact: Jesica Byrne · 602-952-0002 · jessica.byrne@abrazohealth.com
Los Robles Hospital & Medical Center
Thousand Oaks, CA 91360
Site contact: Jason Yashar · 805-796-5881 · jason.yashar@hcahealthcare.com
Yale New Haven Hospital
New Haven, CT 06510
Site contact: Scott Ardito · 203-737-3570 · scott.ardito@yale.edu
Emory University Hospital Midtown
Atlanta, GA 30308
Site contact: Maria Kaner · 404-313-6971 · maria.kaner@emory.edu
Northwestern Memorial Hospital
Chicago, IL 60611
Site contact: Maggie McNamara · 312-926-0846 · margaret.mcnamara@nm.org
Abbott Northwestern Hospital
Minneapolis, MN 55407
Site contact: Jennifer Nguyen · 612-863-9291 · jennifer.nguyen@allina.com
Buffalo General Medical Center
Buffalo, NY 14203
Site contact: Cassandra Davern · 716-881-8299 · cadavern@buffalo.edu
Northwell Health North Shore University Hospital
Manhasset, NY 11030
Site contact: Samantha Annunziato · 516-562-2653 · sannunziato@northwell.edu
NYU Langone Medical Center
New York, NY 10016
Site contact: Sara Hanahan · 929-989-5764 · sara.hanahan@nyulangone.org
Montefiore Medical Center
New York, NY 10467
Site contact: Angela Yang · 718-920-6431 · anyang@montefiore.org
The Christ Hospital
Cincinnati, OH 45219
Site contact: Jamie Elkins · 513-585-1640 · jamie.elkins@thechristhospital.com
Cleveland Clinic Foundation
Cleveland, OH 44195
Site contact: Toni Zimmerman · 216-444-6452 · zimmert5@ccf.org
Study contacts (from the official record)
- Amber St Martin · 612-380-5637 · rs.pathfinder@medtronic.com