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RecruitingAccepts healthy volunteersPhase 2

UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy

University of Alabama at Birmingham · with National Institute on Aging (NIA) · NCT03503331

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 50+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 2
Target enrollment
160
US sites recruiting
1
Study start
April 20, 2018
Record last updated
August 12, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic amyloid deposition using the PET tracer [C-11]PiB in participants in the UAB Alzheimer's Disease Center cohort. Assessment of interactions between race and vascular risk factors, brain amyloid levels measured with [C-11]PiB-PET, and cognitive status will be the primary outcome of this imaging study.

Being studied: [C-11]PiB-PET/MRI

Conditions: Alzheimer Disease

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • 1. Enrollment in the UAB-ADC study under a separate IRB-approved research protocol (IRB-300000169).
  • Negative urine or serum B-hCG test within 2 days of [C-11]PiB administration in women of child bearing potential. Women who are post-menopausal with at least 1 year since last menses or documented surgical sterilization will not require pregnancy testing.

Exclusion Criteria

  • Meets any exclusion criteria for the UAB-ADC study (IRB-300000169).
  • Inability or contraindication for undergoing MRI and/or PET imaging
  • Inability to participate in the imaging studies due to severity of dementia

Recruiting US locations

  • University of Alabama at Birmingham Medical Center

    Birmingham, AL 35294

    Site contact: Jonathan McConathy, MD · 205-996-7115 · jmcconathy@uabmc.edu

Study contacts (from the official record)

  • Chinara Dosse · (205) 975-7017 · cdosse@uabmc.edu
  • Evan Hudson · 205-934-6499 · evanhudson@uabmc.edu
All neurology studies in Alabama →
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy (NCT03503331) | Bored Studies