UnityPhilly Response App for Overdose Reversal
Drexel University · with University of Michigan · NCT06466005
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 450
- US sites recruiting
- 1
- Study start
- September 16, 2025
- Record last updated
- July 20, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The goal of this clinical trial is to discover if an overdose prevention app (UnityPhilly) can encourage citizen responders to respond and prevent opioid overdoses using the UnityPhilly app. The main hypotheses to answer are:
Hypothesis 1: UnityPhilly signal rates relative to EMS calls will increase over time. The primary outcome will be assessed as the total number of overdoses signaled by participants relative to all overdose-related EMS calls, per year.
Hypothesis 2: The number of cases where a nearby UnityPhilly participant successfully reverses an overdose with naloxone will increase over time. The primary outcome will be assessed as the number of successful reversals relative to the total number of responder arrivals, per year.
Participants will be supplied with the UnityPhilly app, training on how to use the app and respond to an opioid overdose using naloxone, and respond to follow up surveys about their experiences.
Being studied: UnityPhilly app
Conditions: Opioid Overdose
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- owning a smartphone with a data package;
- living or working in one of three identified Philadelphia neighborhoods;
- aged 18 or older.
Exclusion Criteria
- persons aged under 18 years of age
Recruiting US locations
Drexel University
Philadelphia, PA 19104
Site contact: Stephen Lankenau, PhD · 323-326-6438 · sel59@drexel.edu
Study contacts (from the official record)
- Stephen Lankenau, PhD · 323-326-6438 · sel59@drexel.edu
- Kushal Naik, MPH · kun24@drexel.edu
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