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UnityPhilly Response App for Overdose Reversal

Drexel University · with University of Michigan · NCT06466005

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
450
US sites recruiting
1
Study start
September 16, 2025
Record last updated
July 20, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this clinical trial is to discover if an overdose prevention app (UnityPhilly) can encourage citizen responders to respond and prevent opioid overdoses using the UnityPhilly app. The main hypotheses to answer are:

Hypothesis 1: UnityPhilly signal rates relative to EMS calls will increase over time. The primary outcome will be assessed as the total number of overdoses signaled by participants relative to all overdose-related EMS calls, per year.

Hypothesis 2: The number of cases where a nearby UnityPhilly participant successfully reverses an overdose with naloxone will increase over time. The primary outcome will be assessed as the number of successful reversals relative to the total number of responder arrivals, per year.

Participants will be supplied with the UnityPhilly app, training on how to use the app and respond to an opioid overdose using naloxone, and respond to follow up surveys about their experiences.

Being studied: UnityPhilly app

Conditions: Opioid Overdose

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • owning a smartphone with a data package;
  • living or working in one of three identified Philadelphia neighborhoods;
  • aged 18 or older.

Exclusion Criteria

  • persons aged under 18 years of age

Recruiting US locations

  • Drexel University

    Philadelphia, PA 19104

    Site contact: Stephen Lankenau, PhD · 323-326-6438 · sel59@drexel.edu

Study contacts (from the official record)

  • Stephen Lankenau, PhD · 323-326-6438 · sel59@drexel.edu
  • Kushal Naik, MPH · kun24@drexel.edu
UnityPhilly Response App for Overdose Reversal (NCT06466005) | Bored Studies