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RecruitingAccepts healthy volunteersPhase 4

Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Weill Medical College of Cornell University · NCT03218137

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–70 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 4
Target enrollment
100
US sites recruiting
1
Study start
February 13, 2017
Record last updated
June 23, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.

Being studied: Adenosine

Conditions: Premature Ventricular Contraction (PVC)

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Diagnosis of premature ventricular contractions (PVCs)
  • Scheduled to undergo an electrophysiology study with the intention of performing cardiac ablation for the treatment of PVCs
  • Male or female between the ages of 18 and 70 years
  • Capable of giving informed consent

Exclusion Criteria

  • Any structural heart disease
  • Coronary artery disease (≥ 70% stenosis)
  • Current treatment with anti-arrhythmic drugs
  • Pregnant
  • Asthma (if administering adenosine)

Recruiting US locations

  • Weill Cornell Medicine

    New York, NY 10065

    Site contact: Dolores T Reynolds, BSN · 212 746 4617 · dtr2001@med.cornell.edu

Study contacts (from the official record)

  • James E Ip, M.D · 212 746 2158 · jei9008@med.cornell.edu
  • Dolores T Reynolds, BSN · 212 746 4617 · dtr2001@med.cornell.edu
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Use of Adenosine to Determine the Electrophysiological Mechanism… (NCT03218137) | Bored Studies