Vagus Nerve Stimulation for Myelopathy
Washington University School of Medicine · NCT07660250
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 36
- US sites recruiting
- 1
- Study start
- April 14, 2026
- Record last updated
- June 22, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The objective of this study is to generate preliminary data to establish the feasibility and effectiveness of transauricular vagus nerve stimulation (taVNS) to improve post-operative outcomes of moderate to severe degenerative cervical myelopathy (DCM)
Being studied: Vagus nerve stimulation (taVNS); Sham Stimulation
Conditions: Degenerative Cervical Myelopathy
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- 18 years of age or older
- Moderate or severe degenerative cervical myelopathy according to the mJOA
- Decompression surgery planned
Exclusion Criteria
- • Pregnancy
- Electrically active implants (e.g. pacemaker)
- Known diagnosis of amyotrophic lateral sclerosis, multiple sclerosis, rheumatoid arthritis, concomitant thoracic and/or lumbar stenosis, spine tumor, HIV-related myelopathy
- Ongoing cancer therapy
- Ongoing use of immunomodulating or suppressive medication
- Sustained bradycardia with a heartrate \<50 beats per minute for > 5 minutes following admission.
- Prior cervical spine surgery
Recruiting US locations
Washington University
St Louis, MO 63110
Site contact: Linda Z Koester, BS · 314-362-7368 · koesterl@wustl.edu
Study contacts (from the official record)
- Linda Koester, BS · 314-362-7368 · koesterl@wustl.edu
Similar studies in Missouri
All healthy volunteers studies in Missouri →- RecruitingHealthy volunteersPhase 1
A Study of V132 in Healthy Older Participants (V132-001)
Merck Sharp & Dohme LLC
- Location
- Springfield, MO + 9 other US sites
- Eligibility basics
- Ages 50–75
- RecruitingHealthy volunteersPhase 1
A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)
Merck Sharp & Dohme LLC
- Location
- Springfield, MO + 5 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HTX-001
Haya Therapeutics, Inc.
- Location
- Kansas City, MO + 1 other US site
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Merck Sharp & Dohme LLC
- Location
- St Louis, MO + 14 other US sites
- Eligibility basics
- Ages 2 mo–1