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Validation of NAD+ Measurements for Human Clinical Studies

University of Pennsylvania · with National Institute on Aging (NIA) · NCT07416786

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–110 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
48
US sites recruiting
1
Study start
September 1, 2026
Record last updated
September 11, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to determine nicotinamide adenine dinucleotide (NAD) levels in healthy adult subjects before and after supplementing with over-the counter nicotinamide riboside (NR) using magnetic resonance spectroscopy (MRS).

Being studied: Oral NR Supplementation

Conditions: Healthy Adults

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria
  • Male or female age18-35 years or 70 years or older, healthy
  • if female reproductive potential, use of highly effective contraception (at least 1 month prior to screening and during study participation).
  • No known sensitivity to NR
  • No use of niacin, blood thinners or chemotherapy agents
  • HbA1c below 8.5% and not diabetec requiring insulin.
  • Not using/taking corticosteroids
  • No laboratory abnormalities indicating significant anemia, bleeding risk, kidney disease, or liver disease
  • No contraindication to MRI
  • Not Pregnant, lactating, or planning to become pregnant during participation
  • Not taking multivitamins or any over-the-counter supplements except calcium and vitamin D (any other supplements - discontinued 2 weeks prior to study participation).
  • not taking/ undergoing another investigational drug or other intervention within the past 30 days.

Recruiting US locations

  • Penn Medicine

    Philadelphia, PA 19104-6006

    Site contact: Mark Elliott, Ph.D · 215-898-8648 · melliott@upenn.edu

Study contacts (from the official record)

  • Damodar Reddy · 215-898-9357 · cdamodar@pennmedicine.upenn.edu
  • Jordan Maddox, BA · 215-898-3694 · jordan.maddox@pennmedicine.upenn.edu
All healthy volunteers studies in Pennsylvania →
Validation of NAD+ Measurements for Human Clinical Studies (NCT07416786) | Bored Studies