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Vapocoolant Spray to Reduce Pain With Nexplanon Insertion

Queen's Medical Center · with Lakshmi Devi and Devraj Sharma Endowment · NCT06933381

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 14+ · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
70
US sites recruiting
2
Study start
June 16, 2025
Record last updated
October 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to assess if Pain Ease vapocoolant spray decreases pain associated with lidocaine injection during Nexplanon insertion procedures.

Being studied: Vapocoolant spray; Placebo

Conditions: Reducing Pain With Nexplanon Implant Insertion

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • At least 14 years or older
  • Undergoing an etonogestrel implant insertion in the arm in POB1 Suite 1004 or POB2 Suite 402
  • English speaking
  • Able and willing to sign the informed consent form and agree to terms of the study

Exclusion Criteria

  • Required or requested narcotics, anxiolytics, IV sedation, or general anesthesia for the procedure
  • Known previous exposure to vapocoolant spray
  • Nexplanon removal and reinsertion same day during visit in the same arm
  • Contraindications to vapocoolant spray components (ethyl chloride and 1,1,1,3,3-pentafluoropropane/1,1,1,2-tetrafluroethane)
  • Unable to provide written, informed consent in English

Recruiting US locations

  • Queens Medical Center POB 2 Suite 402

    Honolulu, HI 96813

    Site contact: Sarah Murayama, MD · 808-783-0298 · smura@hawaii.edu

  • Queens Medical Center POB1 Clinic 1004

    Honolulu, HI 96813

    Site contact: Sarah Murayama, MD · 808-783-0298 · smura@hawaii.edu

Study contacts (from the official record)

  • Sarah Murayama, MD · 808-783-0298 · smura@hawaii.edu
  • Mary Tschann, PhD · 808-375-3785 · mtschann@hawaii.edu
All women’s health studies in Hawaii →
Vapocoolant Spray to Reduce Pain With Nexplanon Insertion (NCT06933381) | Bored Studies