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Wayfinding Intervention and Long-Term Memory

University of California, San Francisco · NCT05625425

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 60–85 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
200
US sites recruiting
1
Study start
January 1, 2024
Record last updated
May 7, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.

Being studied: LabyrinthVR software; Placebo Games software; Labyrinth Tablet software; Labyrinth VR wireless

Conditions: Long-Term Memory Decline; Mild Cognitive Impairment

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • fluent speakers of English
  • completed 12 or more years of education
  • normal or corrected-to-normal vision
  • dexterity to comfortably operate the scanner-compatible response box
  • freedom from physical and neurological conditions contra-indicated for fMRI
  • must confirm physical stamina and comfort for semi-weekly brisk 30-minute walks on level ground

Exclusion Criteria

  • use of psychotropic medications
  • history of concussions or dizziness, vestibular or balance problems
  • significant discomfort with virtual reality experiences

Recruiting US locations

  • UCSF Mission Bay

    San Francisco, CA 94158

    Site contact: Melissa Arioli · 415-502-7321 · twist.study@ucsf.edu

Study contacts (from the official record)

  • Melissa Arioli · 415-502-7321 · twist.study@ucsf.edu
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Wayfinding Intervention and Long-Term Memory (NCT05625425) | Bored Studies