Location · Durham, NC
Clinical trials in Durham, NC
245 recruiting studies have a site in Durham, and 95 of them accept healthy volunteers.
245 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
Epygenix
- Location
- Durham, NC + 16 other US sites
- Eligibility basics
- Ages 2–55
- RecruitingPhase 2
An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy
Teva Branded Pharmaceutical Products R&D LLC
- Location
- Durham, NC + 9 other US sites
- Eligibility basics
- Ages 30+
- Recruiting
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE
Tissium
- Location
- Durham, NC + 7 other US sites
- Eligibility basics
- Ages 22+
- Recruiting
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
W.L.Gore & Associates
- Location
- Durham, NC + 20 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 3
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.
- Location
- Durham, NC + 44 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Xenon Pharmaceuticals Inc.
- Location
- Durham, NC + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults
Regeneron Pharmaceuticals
- Location
- Durham, NC + 17 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder
Pulvinar Neuro, LLC
- Location
- Durham, NC
- Eligibility basics
- Ages 22+
- RecruitingPhase 2/Phase 3
(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
Blueprint Medicines Corporation
- Location
- Durham, NC + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED
Dompé Farmaceutici S.p.A
- Location
- Durham, NC + 15 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Alleviant ALLAY-HFrEF Study
Alleviant Medical, Inc.
- Location
- Durham, NC + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Spyre Therapeutics, Inc.
- Location
- Durham, NC + 25 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Hoffmann-La Roche
- Location
- Durham, NC + 52 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 2
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
Kymera Therapeutics, Inc.
- Location
- Durham, NC + 30 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
Appello Pharmaceuticals, Inc.
- Location
- Durham, NC + 29 other US sites
- Eligibility basics
- Ages 30–80
- RecruitingPhase 4
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Supernus Pharmaceuticals, Inc.
- Location
- Durham, NC + 38 other US sites
- Eligibility basics
- Ages 4–5
- RecruitingPhase 2
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Novo Nordisk A/S
- Location
- Durham, NC + 16 other US sites
- Eligibility basics
- Ages 40–84
- Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Boston Scientific Corporation
- Location
- Durham, NC + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
Disc Medicine, Inc
- Location
- Durham, NC + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Kardigan, Inc.
- Location
- Durham, NC + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
CAR-T Long Term Follow Up (LTFU) Study
Novartis Pharmaceuticals
- Location
- Durham, NC + 38 other US sites
- Eligibility basics
- Ages 0 mo–100
- RecruitingPhase 1/Phase 2
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Sumitomo Pharma America, Inc.
- Location
- Durham, NC + 29 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
ELEVATE-HFpEF Clinical Study
Medtronic Cardiac Rhythm and Heart Failure
- Location
- Durham, NC + 25 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2
A Study of TYRA-300 in Children With Achondroplasia: BEACH301
Tyra Biosciences, Inc
- Location
- Durham, NC + 11 other US sites
- Eligibility basics
- Ages 3–10