Location · Durham, NC
Clinical trials in Durham, NC
245 recruiting studies have a site in Durham, and 95 of them accept healthy volunteers.
245 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
IAP-086-1: A Phase 1 Single Ascending Dose First-Time in Human Study
University of North Carolina, Chapel Hill
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1Overnight stay mentioned
A Study of GNTI-122 in Adults Recently Diagnosed With T1D
GentiBio, Inc
- Location
- Durham, NC + 8 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
pH1N1 Blinded Challenge Study
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Role of Alpha-to-beta Cell Communication to Adapt Insulin Secretion to Insulin Resistance.
David D'Alessio, M.D.
- Location
- Durham, NC
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
Macrophage Regulation of Ozone-Induced Lung Inflammation
Robert Tighe, MD
- Location
- Durham, NC
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–21
- RecruitingHealthy volunteersPhase 3
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
Pfizer
- Location
- Durham, NC + 101 other US sites
- Eligibility basics
- Ages 1 mo–7 mo
- RecruitingHealthy volunteersPhase 3
A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose
Pfizer
- Location
- Durham, NC + 76 other US sites
- Eligibility basics
- Ages 0 mo+
- RecruitingHealthy volunteersPhase 3
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
Pfizer
- Location
- Durham, NC + 111 other US sites
- Eligibility basics
- Ages 0 mo–49
- RecruitingHealthy volunteers
Identifying Patterns in the Breath of Individuals With Breast Cancer
Breathe BioMedical Inc
- Location
- Durham, NC + 2 other US sites
- Eligibility basics
- Ages 40–74 · Women only
- RecruitingHealthy volunteersPhase 3
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
GlaxoSmithKline
- Location
- Durham, NC + 130 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Observational Pharmaco-Epidemiology Research & Analysis
Epividian
- Location
- Durham, NC
- Eligibility basics
- Ages 0 mo+
- RecruitingHealthy volunteersPhase 4
A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age
BioNTech SE
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteers
APOL1 Genotyping CTA Clinical Performance Study
Almac Diagnostic Services LLC
- Location
- Durham, NC
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 2
Study to Evaluate the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections
OsteoRemedies, LLC
- Location
- Durham, NC + 2 other US sites
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteers
Aimovig Pregnancy Exposure Registry
Amgen
- Location
- Durham, NC
- Eligibility basics
- Ages 18–99 · Women only
- RecruitingHealthy volunteers
Registry of Arthrex Hand and Wrist Products
Arthrex, Inc.
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Treatment to Lift Facial Lax Skin and Improve Facial Wrinkles Using Precise and Lift Applicators
Sofwave Medical LTD
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 35–80
- RecruitingHealthy volunteers
Project Mountain - Comparing SpO2 and SaO2 for Accuracy
Philips Clinical & Medical Affairs Global
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Encoded Therapeutics
- Location
- Durham, NC + 9 other US sites
- Eligibility basics
- Ages 6 mo–17
- RecruitingPhase 3
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Hoffmann-La Roche
- Location
- Durham, NC + 121 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Hoffmann-La Roche
- Location
- Durham, NC + 112 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study
W.L.Gore & Associates
- Location
- Durham, NC + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation
Biogen
- Location
- Durham, NC + 24 other US sites
- Eligibility basics
- Ages 18–74