Location · Durham, NC
Clinical trials in Durham, NC
245 recruiting studies have a site in Durham, and 95 of them accept healthy volunteers.
245 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Rocket Pharmaceuticals Inc.
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia
ReAlta Life Sciences, Inc.
- Location
- Durham, NC + 13 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 3
A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)
Merck Sharp & Dohme LLC
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
- Location
- Durham, NC + 36 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 1/Phase 2
A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study
ModernaTX, Inc.
- Location
- Durham, NC + 5 other US sites
- Eligibility basics
- Ages 1+
- Recruiting
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
XVIVO Perfusion
- Location
- Durham, NC + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)
Direct Biologics, LLC
- Location
- Durham, NC + 30 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia
Karyopharm Therapeutics Inc
- Location
- Durham, NC + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia
ModernaTX, Inc.
- Location
- Durham, NC + 7 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 3
A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18
Amicus Therapeutics
- Location
- Durham, NC + 5 other US sites
- Eligibility basics
- Up to age 17
- RecruitingPhase 3
A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Takeda
- Location
- Durham, NC + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Enhancing Heart Allograft Function With the OCS Heart System Trial
TransMedics
- Location
- Durham, NC + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Neurona Therapeutics
- Location
- Durham, NC + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery
Pacira Pharmaceuticals, Inc
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Ages 0 mo–6
- RecruitingPhase 3
Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2
ReGenTree, LLC
- Location
- Durham, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)
Deciphera Pharmaceuticals, LLC
- Location
- Durham, NC + 25 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
Mezzion Pharma Co. Ltd
- Location
- Durham, NC + 34 other US sites
- Eligibility basics
- Ages 12–18
- RecruitingPhase 3
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
Kartos Therapeutics, Inc.
- Location
- Durham, NC + 57 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
Sumitomo Pharma Switzerland GmbH
- Location
- Durham, NC + 101 other US sites
- Eligibility basics
- Ages 18–50 · Women only
- RecruitingPhase 3
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
SK Life Science, Inc.
- Location
- Durham, NC + 6 other US sites
- Eligibility basics
- Ages 4–55
- RecruitingPhase 2
A Phase 2a Proof of Concept Open-Label, Randomized, Controlled Study to Evaluate the Safety and Efficacy of MDI-1228-mesylate Gel Compared With Standard of Care Alone in Patients With Diabetic Foot Ulcers
Zhuhai Rui-Inno Pharmaceutical Technology Co., Ltd.
- Location
- Durham, NC
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).
NorthSea Therapeutics B.V.
- Location
- Durham, NC + 11 other US sites
- Eligibility basics
- Ages 16+
- Recruiting
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
XSpline S.p.A.
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
Sardocor Corp.
- Location
- Durham, NC
- Eligibility basics
- Ages 50+