Location · South Dakota
Clinical trials recruiting in South Dakota
70 recruiting studies have at least one site in South Dakota; 12 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in South Dakota.
70 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Hoffmann-La Roche
- Location
- Sioux Falls, SD + 44 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
AstraZeneca
- Location
- Rapid City, SD + 53 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Eli Lilly and Company
- Location
- Sioux Falls, SD + 38 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of Brenipatide in Participants With Opioid Use Disorder
Eli Lilly and Company
- Location
- Sioux Falls, SD + 35 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED
Dompé Farmaceutici S.p.A
- Location
- Sioux Falls, SD + 15 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Alleviant ALLAY-HFrEF Study
Alleviant Medical, Inc.
- Location
- Rapid City, SD + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Hoffmann-La Roche
- Location
- Sioux Falls, SD + 52 other US sites
- Eligibility basics
- Ages 50–85
- Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Boston Scientific Corporation
- Location
- Sioux Falls, SD + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Eli Lilly and Company
- Location
- Sioux Falls, SD + 31 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
Nectero EAST System Clinical Study
Nectero Medical, Inc.
- Location
- Sioux Falls, SD + 35 other US sites
- Eligibility basics
- Ages 21–85
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Crystalys Therapeutics
- Location
- Rapid City, SD + 81 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Crystalys Therapeutics
- Location
- Rapid City, SD + 82 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Ambulatory Long Length URodynamics Evaluation
Bright Uro
- Location
- Sioux Falls, SD + 8 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 2
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
Eli Lilly and Company
- Location
- Sioux Falls, SD + 16 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Takeda
- Location
- Rapid City, SD + 36 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Cumberland Pharmaceuticals
- Location
- Sioux Falls, SD + 17 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material
EmStop Inc
- Location
- Rapid City, SD + 6 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
A Study of Depemokimab in Participants of 6 to 11 Years of Age
GlaxoSmithKline
- Location
- Watertown, SD + 2 other US sites
- Eligibility basics
- Ages 6–11
- RecruitingPhase 3
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
GlaxoSmithKline
- Location
- Rapid City, SD + 13 other US sites
- Eligibility basics
- Ages 12+
- Recruiting
xDot Access Management System Early Feasibility Study
xDot Medical, Inc
- Location
- Sioux Falls, SD + 4 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Alleviant ALLAY-HF Study
Alleviant Medical, Inc.
- Location
- Rapid City, SD + 42 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
BOOM-IBD2 Pivotal Clinical Trial
Boomerang Medical
- Location
- Sioux Falls, SD + 15 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2
Study of WAL0921 in Patients With Glomerular Kidney Diseases
Walden Biosciences
- Location
- Dakota Dunes, SD + 8 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis
Aurinia Pharmaceuticals Inc.
- Location
- Dakota Dunes, SD + 26 other US sites
- Eligibility basics
- Ages 18–75