Location · South Dakota
Clinical trials recruiting in South Dakota
70 recruiting studies have at least one site in South Dakota; 12 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in South Dakota.
70 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
Ecotera Health LLC
- Location
- Sioux Falls, SD + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Helix Research Network
Helix, Inc
- Location
- Sioux Falls, SD + 13 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Assessment of CCM in HF With Higher Ejection Fraction
Impulse Dynamics
- Location
- Sioux Falls, SD + 64 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
Merck Sharp & Dohme LLC
- Location
- Sioux Falls, SD + 70 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 3
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular…
AbbVie
- Location
- Rapid City, SD + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
AstraZeneca
- Location
- Rapid City, SD + 58 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 3
Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease
Regeneron Pharmaceuticals
- Location
- Rapid City, SD + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Pfizer
- Location
- Rapid City, SD + 58 other US sites
- Eligibility basics
- Ages 35–80
- RecruitingPhase 2
A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)
Novartis Pharmaceuticals
- Location
- Sioux Falls, SD + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
Regeneron Pharmaceuticals
- Location
- Rapid City, SD + 41 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
CVRx, Inc.
- Location
- Sioux Falls, SD + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
Takeda
- Location
- Sioux Falls, SD + 77 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease
ADARx Pharmaceuticals, Inc.
- Location
- Dakota Dunes, SD + 6 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device
MedtronicNeuro
- Location
- Sioux Falls, SD + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Sanofi
- Location
- Sioux Falls, SD + 72 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 3
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With…
Amgen
- Location
- Rapid City, SD + 73 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
NORM-HF Pivotal Study
Foundry Innovation & Research 1, Limited (FIRE1)
- Location
- Sioux Falls, SD + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
Pfizer
- Location
- Sioux Falls, SD + 28 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 3
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Boehringer Ingelheim
- Location
- Rapid City, SD + 91 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
Regeneron Pharmaceuticals
- Location
- Rapid City, SD + 42 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
AstraZeneca
- Location
- Rapid City, SD + 93 other US sites
- Eligibility basics
- Ages 18–130
- RecruitingPhase 3
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
AstraZeneca
- Location
- Sioux Falls, SD + 70 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 3
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Cytokinetics
- Location
- Rapid City, SD + 80 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Hoffmann-La Roche
- Location
- Sioux Falls, SD + 43 other US sites
- Eligibility basics
- Ages 18+