Heart & blood pressure · Missouri
Heart and blood pressure studies in Missouri
81 studies have at least one recruiting site in Missouri. Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
81 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
ELEVATE High-Risk PCI Pivotal Study
Magenta Medical Ltd.
- Location
- Kansas City, MO + 32 other US sites
- Eligibility basics
- Ages 18–88
- RecruitingPhase 3
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Amgen
- Location
- City of Saint Peters, MO + 136 other US sites
- Eligibility basics
- Ages 45–99
- RecruitingPhase 3
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Eli Lilly and Company
- Location
- Springfield, MO + 68 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Merck Sharp & Dohme LLC
- Location
- St Louis, MO + 7 other US sites
- Eligibility basics
- Ages 6–17
- Recruiting
Zenith® Fenestrated+ Clinical Study
Cook Research Incorporated
- Location
- St Louis, MO + 29 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Alleviant ALLAY-HFrEF Study
Alleviant Medical, Inc.
- Location
- St Louis, MO + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals
- Location
- St Louis, MO
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Novo Nordisk A/S
- Location
- St Louis, MO + 16 other US sites
- Eligibility basics
- Ages 40–84
- RecruitingPhase 2/Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Kardigan, Inc.
- Location
- Kansas City, MO + 26 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
ELEVATE-HFpEF Clinical Study
Medtronic Cardiac Rhythm and Heart Failure
- Location
- Kansas City, MO + 25 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Retension Pharmaceuticals. Inc.
- Location
- Overland, MO + 31 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Shockwave Medical, Inc.
- Location
- Kansas City, MO + 66 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
35Pharma Inc
- Location
- Kansas City, MO + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
Genentech, Inc.
- Location
- St Louis, MO + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
AstraZeneca
- Location
- Kansas City, MO + 104 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Edwards Lifesciences
- Location
- St Louis, MO + 30 other US sites
- Eligibility basics
- Any age listed
- Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
SoniVie Inc.
- Location
- Kansas City, MO + 33 other US sites
- Eligibility basics
- Ages 22–75
- RecruitingPhase 2
A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis
Beijing Inno Medicine Co., Ltd.
- Location
- St Louis, MO
- Eligibility basics
- Ages 18–80
- Recruiting
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
Axon Therapies, Inc.
- Location
- St Louis, MO + 15 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 1/Phase 2
ATR 1072 in Participants With PRKAG2 Syndrome
Atrium Therapeutics
- Location
- Kansas City, MO
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen
- Location
- Kansas City, MO + 117 other US sites
- Eligibility basics
- Ages 18–99
- Recruiting
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Medtronic Cardiovascular
- Location
- St Louis, MO + 68 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
BrioHealth Solutions, Inc.
- Location
- St Louis, MO + 46 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 2
Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
Marea Therapeutics
- Location
- St Louis, MO + 6 other US sites
- Eligibility basics
- Ages 18–75
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.