Heart & blood pressure · Missouri
Heart and blood pressure studies in Missouri
81 studies have at least one recruiting site in Missouri. Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
81 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Inhibikase Therapeutics
- Location
- St Louis, MO + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Merck Sharp & Dohme LLC
- Location
- St Louis, MO + 19 other US sites
- Eligibility basics
- Ages 1 mo–17
- RecruitingPhase 2
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
Cytokinetics
- Location
- St Louis, MO + 23 other US sites
- Eligibility basics
- Ages 40–85
- Recruiting
Alleviant ALLAY-HF Study
Alleviant Medical, Inc.
- Location
- St Louis, MO + 42 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Eidos Therapeutics, a BridgeBio company
- Location
- Kansas City, MO + 39 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Novartis Pharmaceuticals
- Location
- Jefferson City, MO + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis
Eidos Therapeutics, a BridgeBio company
- Location
- St Louis, MO
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- St Louis, MO + 3 other US sites
- Eligibility basics
- Ages 2–11
- Recruiting
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Teleflex
- Location
- St Louis, MO + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Anthos Therapeutics, Inc.
- Location
- Kansa City, MO + 131 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- St Louis, MO + 46 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Endotronix, Inc.
- Location
- Kansas City, MO + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
DalCor Pharmaceuticals
- Location
- St Louis, MO + 112 other US sites
- Eligibility basics
- Ages 45+
- Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
- Location
- Kansas City, MO + 56 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.
- Location
- St Louis, MO + 19 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Medtronic Terminate AF Study
Medtronic Cardiac Surgery
- Location
- St Louis, MO + 6 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Cardiac Dimensions, Inc.
- Location
- St Louis, MO + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
- Location
- Kansas City, MO + 36 other US sites
- Eligibility basics
- Ages 18–90
- Recruiting
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
XVIVO Perfusion
- Location
- St Louis, MO + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
Vanda Pharmaceuticals
- Location
- Hazelwood, MO + 17 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Edwards Lifesciences
- Location
- Kansas City, MO + 49 other US sites
- Eligibility basics
- Ages 65+
- Recruiting
Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR
EnCompass Technologies, Inc.
- Location
- Kansas City, MO + 4 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
Mezzion Pharma Co. Ltd
- Location
- Kansas City, MO + 34 other US sites
- Eligibility basics
- Ages 12–18
- Recruiting
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
Endospan Ltd.
- Location
- St Louis, MO + 23 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.