Mental health · Cleveland area, OH
Mental health studies in Cleveland area, OH
19 recruiting studies have a site in the Cleveland area. This page includes nearby cities such as Beachwood, Mayfield Heights, Independence, Westlake.
19 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Abbott Medical Devices
- Location
- Cleveland, OH + 24 other US sites
- Eligibility basics
- Ages 22–70
- RecruitingPhase 3
A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
Vericel Corporation
- Location
- Akron, OH + 10 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingPhase 2
ALTO-100 in Bipolar Disorder With Depression (BD-D)
Alto Neuroscience
- Location
- Cincinnati, OH + 38 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study of Brenipatide in Adult Participants With Schizophrenia
Eli Lilly and Company
- Location
- Independence, OH + 31 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
Seaport Therapeutics
- Location
- Independence, OH + 26 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 4
Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
Vanda Pharmaceuticals
- Location
- Cincinnati, OH + 9 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
MapLight Therapeutics
- Location
- Dayton, OH + 32 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.
- Location
- Cleveland, OH + 27 other US sites
- Eligibility basics
- Ages 55–84
- RecruitingPhase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Columbus, OH + 43 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 4
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
Neurocrine Biosciences
- Location
- Independence, OH + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
Transcend Therapeutics
- Location
- Independence, OH + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
52-week Open Label Safety-Tolerability Study
LB Pharmaceuticals Inc.
- Location
- Canton, OH + 22 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Syndeio Biosciences, Inc
- Location
- Independence, OH + 20 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingPhase 3
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
AbbVie
- Location
- Cleveland, OH + 30 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingPhase 2
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
LB Pharmaceuticals Inc.
- Location
- Canton, OH + 25 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Bristol-Myers Squibb
- Location
- Independence, OH + 2 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
Autobahn Therapeutics, Inc.
- Location
- Beachwood, OH + 31 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder
University Hospitals Cleveland Medical Center
- Location
- Cleveland, OH
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
VA Office of Research and Development
- Location
- Cleveland, OH + 8 other US sites
- Eligibility basics
- Ages 40+
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.