Phase 1 · Cleveland area, OH
Phase 1 clinical trials in Cleveland area, OH
25 recruiting studies have a site in the Cleveland area. This page includes nearby cities such as Beachwood, Mayfield Heights, Independence, Westlake.
25 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Blue Lake Biotechnology Inc.
- Location
- Beachwood, OH + 13 other US sites
- Eligibility basics
- Ages 6 mo–5
- RecruitingHealthy volunteersPhase 1
A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)
Merck Sharp & Dohme LLC
- Location
- Cleveland, OH + 5 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Beachwood, OH + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersEarly Phase 1
HA35 Acute Alcohol Study
The Cleveland Clinic
- Location
- Cleveland, OH
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 1
Home-based Vision Therapy
VA Office of Research and Development
- Location
- Cleveland, OH
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion
James Reynolds
- Location
- Cleveland, OH
- Eligibility basics
- Ages 18–35
- RecruitingPhase 1
A Study to Explore the Tissue Level Effects of Remibrutinib in Adults With Moderate to Severe HS
Novartis Pharmaceuticals
- Location
- Mayfield Heights, OH
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Safety and Efficacy of Soquelitinib in Adults With Hidradenitis Suppurativa
Corvus Pharmaceuticals, Inc.
- Location
- Mayfield Heights, OH + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).
Novartis Pharmaceuticals
- Location
- Cincinnati, OH + 10 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 1
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Solid Biosciences Inc.
- Location
- Cleveland, OH + 2 other US sites
- Eligibility basics
- Ages 7+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Biojiva LLC
- Location
- Beachwood, OH + 4 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company, Inc.
- Location
- Cleveland, OH + 44 other US sites
- Eligibility basics
- Ages 12–35
- RecruitingPhase 1
A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc.
- Location
- Cleveland, OH + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.
- Location
- Cleveland, OH + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Study of BHV-1300 in Graves' Disease
Biohaven Therapeutics Ltd.
- Location
- Canton, OH + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
Alexion Pharmaceuticals, Inc.
- Location
- Cleveland, OH + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
Fate Therapeutics
- Location
- Cleveland, OH + 15 other US sites
- Eligibility basics
- Ages 12–70
- RecruitingPhase 1/Phase 2
A Study to Investigate the Improvement of Photosensitivity in Terms of Skin Lesions Associated With CEP Following Administration of Oral ATL-001 (Ciclopirox Oral Solution) in Participants Aged >18 Years of Age With CEP
Atlas Molecular Pharma
- Location
- Cleveland, OH
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Tenaya Therapeutics
- Location
- Cleveland, OH + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
U: The Mind Company
- Location
- Cleveland, OH
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1/Phase 2
Treatment of Moderate to Severe Refractory Crohn's Disease
Tr1X, Inc.
- Location
- Cleveland, OH + 12 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics
PharmaIN
- Location
- Cleveland, OH + 8 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL
Ascentage Pharma Group Inc.
- Location
- Canton, OH + 6 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Tenaya Therapeutics
- Location
- Cleveland, OH + 6 other US sites
- Eligibility basics
- Ages 18–65
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.