Mental health · Ohio
Mental health studies in Ohio
66 studies have at least one recruiting site in Ohio. Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
66 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Bristol-Myers Squibb
- Location
- Independence, OH + 2 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
AbbVie
- Location
- Avon Lake, OH + 46 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
AbbVie
- Location
- Avon Lake, OH + 32 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Monument Therapeutics Limited
- Location
- Columbus, OH + 14 other US sites
- Eligibility basics
- Ages 17–30
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
atai Therapeutics, Inc.
- Location
- Columbus, OH + 33 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
ALTO-207 in Adults With Treatment-resistant Depression (TRD)
Alto Neuroscience
- Location
- Cincinnati, OH + 11 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
Autobahn Therapeutics, Inc.
- Location
- Beachwood, OH + 31 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Avon Lake, OH + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of ALTO-300 in MDD
Alto Neuroscience
- Location
- Cincinnati, OH + 36 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
EEG-based Personalized Transcranial Magnetic Stimulation (eTMS) to Treat Post-Traumatic Stress Disorder
Wave Neuroscience
- Location
- Dayton, OH + 1 other US site
- Eligibility basics
- Ages 22–65
- RecruitingPhase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Axsome Therapeutics, Inc.
- Location
- Cincinnati, OH + 36 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Virtual Reality Viewing of Unaltered Streetscape Versus Digitally Manipulated Opposite Streetscape to Assess Psychosocial Response in Participants
Ohio State University Comprehensive Cancer Center
- Location
- Columbus, OH
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder
University Hospitals Cleveland Medical Center
- Location
- Cleveland, OH
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder
Donald Gilbert, MD, MS, FAAN, FAAP
- Location
- Cincinnati, OH + 1 other US site
- Eligibility basics
- Ages 8–12
- RecruitingHealthy volunteers
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Duke University
- Location
- Cincinnati, OH + 3 other US sites
- Eligibility basics
- Ages 0 mo–20
- RecruitingHealthy volunteersPhase 4
Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
VA Office of Research and Development
- Location
- Cleveland, OH + 8 other US sites
- Eligibility basics
- Ages 40+
- RecruitingHealthy volunteersPhase 4
Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.
University of Cincinnati
- Location
- Cincinnati, OH
- Eligibility basics
- Ages 8–17
- RecruitingHealthy volunteersPhase 4
Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)
University of Cincinnati
- Location
- Cincinnati, OH
- Eligibility basics
- Ages 12–17
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.