Phase 1 · Los Angeles area, CA
Phase 1 clinical trials in Los Angeles area, CA
133 recruiting studies have a site in the Los Angeles area. This page includes nearby cities such as Santa Monica, Beverly Hills, Pasadena, Long Beach.
133 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
Pfizer
- Location
- Cypress, CA
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
Pfizer
- Location
- Anaheim, CA + 9 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1/Phase 2
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Regeneron Pharmaceuticals
- Location
- Los Angeles, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
Evaluate the Pharmacokinetics, Safety, and Tolerability of NSHO-101 in Healthy Participants
Ensho Therapeutics, Inc.
- Location
- Anaheim, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986521 in Healthy Participants.
Bristol-Myers Squibb
- Location
- Anaheim, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
Vega Therapeutics, Inc
- Location
- Los Angeles, CA + 9 other US sites
- Eligibility basics
- Ages 12–60
- RecruitingHealthy volunteersPhase 1/Phase 2
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
Thomas Advanced Medical LLC
- Location
- Culver City, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1Overnight stay mentioned
A Study of GNTI-122 in Adults Recently Diagnosed With T1D
GentiBio, Inc
- Location
- Duarte, CA + 8 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1Overnight stay mentioned
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
BioXcel Therapeutics Inc
- Location
- Anaheim, CA + 3 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingHealthy volunteersPhase 1
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
City of Hope Medical Center
- Location
- Duarte, CA + 2 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
Writing About Experiences and Health in Older Adults II
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersPhase 1
Evaluation of Oral THC and CBD in Men and Women
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteersPhase 1
High Potency Cannabis: Acute and Protracted Effects
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses
Kara Chew
- Location
- Los Angeles, CA + 1 other US site
- Eligibility basics
- Ages 40–64
- RecruitingHealthy volunteersPhase 1/Phase 2
Hyperemesis Gravidarum Risk Reduction With Metformin
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–49 · Women only
- RecruitingHealthy volunteersPhase 1
COES: Curing Order Effects on Sealants
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 5–14
- RecruitingHealthy volunteersEarly Phase 1
CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDS
City of Hope Medical Center
- Location
- Duarte, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Biologic Therapy to Prevent Osteoarthritis After ACL Injury
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–35
- RecruitingHealthy volunteersPhase 1
Age-dependent Effects of Smoked and Oral Delta-9-THC
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent…
City of Hope Medical Center
- Location
- Duarte, CA
- Eligibility basics
- Up to age 75
- RecruitingHealthy volunteersPhase 1
THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteersPhase 1
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Vocal Emotion Communication With Cochlear Implants
Father Flanagan's Boys' Home
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 6–80
- RecruitingPhase 1
Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
Verve Therapeutics, Inc.
- Location
- Garden Grove, CA + 4 other US sites
- Eligibility basics
- Ages 18–70
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.