Phase 1 · Los Angeles area, CA
Phase 1 clinical trials in Los Angeles area, CA
133 recruiting studies have a site in the Los Angeles area. This page includes nearby cities such as Santa Monica, Beverly Hills, Pasadena, Long Beach.
133 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1
A Study of SGT-212 Gene Therapy in Friedreich's Ataxia
Solid Biosciences Inc.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18–40
- RecruitingPhase 1
A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia
Janssen Research & Development, LLC
- Location
- Garden Grove, CA + 7 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
GigaGen, Inc.
- Location
- Huntington Beach, CA + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease
UniQure Biopharma B.V.
- Location
- Los Angeles, CA + 9 other US sites
- Eligibility basics
- Ages 18–65 · Men only
- RecruitingPhase 1/Phase 2
Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)
Opus Genetics, Inc
- Location
- Los Angeles, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study of GS-0415 and How It Works in People With HIV
Gilead Sciences
- Location
- Los Angeles, CA + 14 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
UCB Biopharma SRL
- Location
- Santa Monica, CA + 5 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 1
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
AstraZeneca
- Location
- Fullerton, CA + 2 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
AbbVie
- Location
- Irvine, CA + 10 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 1
A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) - Non-Ambulatory Cohort
Sarepta Therapeutics, Inc.
- Location
- La Jolla, CA + 10 other US sites
- Eligibility basics
- Ages 2+ · Men only
- RecruitingPhase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company, Inc.
- Location
- Newport Beach, CA + 44 other US sites
- Eligibility basics
- Ages 12–35
- RecruitingPhase 1
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
Novo Nordisk A/S
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1
A Study to Evaluate Sequential Administration of Injections of AGN-151586 Followed by BOTOX in Adult Participants for Treatment of Glabellar Lines
AbbVie
- Location
- Newport Beach, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Astellas Institute for Regenerative Medicine
- Location
- Los Angeles, CA + 12 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1
Safety and Feasibility Study of the CELLSPAN Esophageal Implant (CEI) in Patients Requiring Short Segment Esophageal Replacement
Harvard Apparatus Regenerative Technology, Inc.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Biogen
- Location
- Orange, CA + 11 other US sites
- Eligibility basics
- Ages 3+
- RecruitingPhase 1/Phase 2
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent…
Cyllene Therapeutics
- Location
- Downey, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
OM336 in Autoimmune Cytopenias
Lakefront Biotherapeutics West LLC
- Location
- Duarte, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Phase 1 Study Evaluating Safety and Pharmacokinetics of ASY202 in Adults With Asthma
Aspeya, Inc.
- Location
- Anaheim, CA
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1/Phase 2
FT839 in Autoimmune Diseases
Fate Therapeutics
- Location
- Fullerton, CA
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy
CytoAgents, Inc.
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis
CarthroniX, Inc.
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 40–75
- RecruitingPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia
AstraZeneca
- Location
- Glendale, CA + 5 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Cerritos, CA + 78 other US sites
- Eligibility basics
- Ages 18–45
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.