Phase 1 · Los Angeles area, CA
Phase 1 clinical trials in Los Angeles area, CA
133 recruiting studies have a site in the Los Angeles area. This page includes nearby cities such as Santa Monica, Beverly Hills, Pasadena, Long Beach.
133 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)
NGGT INC.
- Location
- Orange, CA + 4 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease
Denali Therapeutics Inc.
- Location
- Irvine, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections
Macro Biologics, Inc.
- Location
- Torrance, CA + 4 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 1
Phase 1 Study of C.001 in Retinal Degeneration
Cellio Therapeutics Inc
- Location
- Beverly Hills, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Nkarta, Inc.
- Location
- Orange, CA + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity
AbbVie
- Location
- Anaheim, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)
Nuevocor Pte. Ltd.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Regeneron Pharmaceuticals
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
Study of Aritinercept in Patients With Generalized Myasthenia Gravis
Aurinia Pharmaceuticals Inc.
- Location
- Pasadena, CA + 9 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1/Phase 2
A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.
Ipsen
- Location
- Downey, CA + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome
MavriX Bio, LLC
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 4–50
- RecruitingPhase 1
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
Chugai Pharmaceutical
- Location
- Orange, CA + 6 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide…
Novo Nordisk A/S
- Location
- Cypress, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA
Neutrolis
- Location
- Apple Valley, CA + 6 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Encino, CA + 3 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 1/Phase 2
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Solid Biosciences Inc.
- Location
- Los Angeles, CA + 11 other US sites
- Eligibility basics
- Ages 0 mo–17 · Men only
- RecruitingPhase 1
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
UCB Biopharma SRL
- Location
- Apple Valley, CA + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease
Kamau Therapeutics
- Location
- Los Angeles, CA + 5 other US sites
- Eligibility basics
- Ages 12–50
- RecruitingEarly Phase 1
VTP-1000 in Adults With Celiac Disease
Barinthus Biotherapeutics
- Location
- Los Angeles, CA + 15 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Monument Therapeutics Limited
- Location
- Irvine, CA + 14 other US sites
- Eligibility basics
- Ages 17–30
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
Nkarta, Inc.
- Location
- Tustin, CA + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)
Exegi Pharma, LLC
- Location
- Los Angeles, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
Fate Therapeutics
- Location
- Beverly Hills, CA + 15 other US sites
- Eligibility basics
- Ages 12–70
- RecruitingPhase 1
Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)
Life Biosciences Inc.
- Location
- Glendale, CA + 3 other US sites
- Eligibility basics
- Ages 40–85
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.